Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.50 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.49 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.49 |
| ▸ | DTYMK | P23919 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | S100A4 | P26447 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27745774 | 0.98 | GPR35 (0.49) | GPR35AKR1C2AKR1C1DTYMKKDM4E | |
| SCHEMBL17875619 | 0.87 | CES2 (0.53) | GPR35AKR1C2AKR1C1KDM4EALDH1A1 | |
| SCHEMBL1228589 | 0.85 | DTYMK (0.62) | GPR35AKR1C2AKR1C1DTYMKKDM4E | |
| SCHEMBL30566926 | 0.85 | DTYMK (0.62) | GPR35AKR1C2AKR1C1DTYMKKDM4E | |
| SCHEMBL30025405 | 0.84 | KDM4E (0.45) | KDM4ES100A4TRPV1CES2PKM | |
| SCHEMBL3911021 | 0.84 | S100A4 (0.44) | GPR35AKR1C2AKR1C1KDM4ETSHR | |
| SCHEMBL3498660 | 0.84 | KDM4E (0.45) | KDM4ES100A4TRPV1CES2PKM | |
| SCHEMBL8232986 | 0.84 | DGAT1 (0.53) | GPR35AKR1C2AKR1C1KDM4ETSHR | |
| SCHEMBL3898845 | 0.82 | MAPT (0.49) | DTYMKKDM4EALDH1A1CYP3A4LMNA | |
| SCHEMBL3434574 | 0.82 | GPR35 (0.51) | GPR35AKR1C2AKR1C1DTYMKKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 468 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114213202-B | Preparation method of 2, 4-substituted benzoic acid | 石河子大学 | 2024-07-05 | — | — | CN | claimed |
| CN-114213202-A | Preparation method of 2, 4-substituted benzoic acid | 石河子大学 | 2022-03-22 | — | — | CN | claimed |
| CN-107417565-B | 4-bromo-N-3, 5-dimethoxyphenylbenzamide derivative acting on FGFR1 and preparation and application thereof | 温州医科大学 | 2020-02-14 | — | — | CN | claimed |
| CN-106187803-A | The synthetic method of the amides compound that a kind of phosphorus oxychloride promotes | 中国人民解放军63975部队 | 2016-12-07 | — | — | CN | claimed |
| CN-105884687-A | Preparation method of 5-benzyl benzydamine | 梯尔希（南京）药物研发有限公司 | 2016-08-24 | — | — | CN | claimed |
| EP-4076459-B1 | PRMT5 INHIBITORS | MERCK SHARP & DOHME LLC (US) | 2026-04-29 | — | — | EP | disclosed |
| US-12595248-B2 | PRMT5 inhibitors | MERCK SHARP & DOHME LLC (US) | 2026-04-07 | — | — | US | disclosed |
| US-12491492-B1 | Photocatalytic degradation and removal of imidacloprid insecticide using hydrophilic magnetic covalent organic frameworks (COFs) | UNITED ARAB EMIRATES UNIVERSITY (AE) | 2025-12-09 | — | — | US | disclosed |
| CN-120058808-A | Metal complex, organic electroluminescent device and application | 安徽宇贝新材料科技有限公司 | 2025-05-30 | — | — | CN | disclosed |
| CN-119841822-A | Pyrimido [5,4-c ] quinoline compound, preparation method, pharmaceutical composition and application thereof | 苏州施安鼎泰生物医药技术有限公司 | 2025-04-18 | — | — | CN | disclosed |
| EP-3956315-B1 | BENZO- AND PYRIDO-PYRAZOLES AS PROTEIN KINASE INHIBITORS | Rottapharm Biotech Srl (IT) | 2025-04-16 | — | — | EP | disclosed |
| EP-3870577-B1 | INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | VIIV HEALTHCARE UK NO 5 LTD (GB) | 2025-03-19 | — | — | EP | disclosed |
| EP-0674629-A1 | 4-BENZOYL ISOXAZOLES DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1995-10-04 | — | — | EP | disclosed |
| CN-1089258-A | New herbicides | RHONE POULENC AGRICULTURE (GB) | 1994-07-13 | — | — | CN | disclosed |
| WO-1994014782-A1 | 4-BENZOYL ISOXAZOLES DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1994-07-07 | — | — | WO | disclosed |
| CN-1017242-B | NEW QUIANZOLINE DERIVATIVES AND PROCESS FOR THEIR PRODUCTION | FUJISAWA PHARMACEUTICAL CO (JP) | 1992-07-01 | — | — | CN | disclosed |
| US-4883800-A | DIABETES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-11-28 | — | — | US | disclosed |
| US-4734419-A | Quinazoline derivatives, compositions thereof and their use in treating diabetic complications | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-29 | — | — | US | disclosed |
| CN-86106984-A | New quinazoline derivant and preparation method thereof | — | 1987-05-20 | — | — | CN | disclosed |
| EP-0218999-A2 | New quinazoline derivatives, process for their production and pharmaceutical compositions comprising them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-04-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12595248-B2 | PRMT5 inhibitors | PRMT5, PRMT1, PRMT6 | GPR35 1423/4885AKR1C2 2634/4885AKR1C1 2210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.