Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.31 |
| ▸ | CETP | P11597 | 1/20 | 0.30 |
| ▸ | CFD | P00746 | 1/20 | 0.30 |
| ▸ | KMO | O15229 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
| ▸ | MPO | P05164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13316641 | 0.89 | CCNT1 (0.34) | CCNT1ALOX5APFEN1CNR2SGMS2 | |
| SCHEMBL13316630 | 0.83 | CCNT1 (0.33) | CCNT1ALOX5APFEN1CNR2SGMS2 | |
| SCHEMBL13349669 | 0.79 | MPO (0.32) | SGMS2KMOMPO | |
| SCHEMBL13316640 | 0.76 | CCNT1 (0.32) | CCNT1CNR2SGMS2CTSKCFD | |
| SCHEMBL13316668 | 0.74 | S1PR3 (0.39) | CNR2CTSK | |
| SCHEMBL13316633 | 0.72 | KDM4C (0.36) | ALOX5APFEN1 | |
| SCHEMBL19208107 | 0.68 | P2RX7 (0.41) | CCNT1CFDP2RX7 | |
| SCHEMBL13316625 | 0.68 | MPO (0.41) | SGMS2P2RX7MPO | |
| SCHEMBL13316666 | 0.67 | S1PR3 (0.40) | CNR2SGMS2CTSK | |
| SCHEMBL13349710 | 0.67 | CXCR2 (0.32) | CNR2METTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7745459-B2 | Quinolizinone compound and use thereof as HIV integrase inhibitor | JAPAN TOBACCO INC. (JP) | 2010-06-29 | — | — | US | disclosed |
| US-7745459-B2 | Quinolizinone compound and use thereof as HIV integrase inhibitor | JAPAN TOBACCO INC. (JP) | 2010-06-29 | — | — | US | disclosed |