Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CASR | P41180 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 2/20 | 0.31 |
| ▸ | CTSK | P43235 | 2/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
| ▸ | CFD | P00746 | 2/20 | 0.30 |
| ▸ | CTSL | P07711 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.30 |
| ▸ | CETP | P11597 | 1/20 | 0.30 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13316640 | 0.89 | CCNT1 (0.32) | CCNT1CASRCNR2SGMS2CTSS | |
| SCHEMBL13316643 | 0.83 | CCNT1 (0.35) | CCNT1CNR2SGMS2CTSKCFD | |
| SCHEMBL13349673 | 0.78 | MPO (0.32) | — | |
| SCHEMBL13316641 | 0.76 | CCNT1 (0.34) | CCNT1CNR2SGMS2CTSKCFD | |
| SCHEMBL21656577 | 0.74 | CTSL (0.36) | CTSSCTSKCTSL | |
| SCHEMBL21656297 | 0.74 | RIPK1 (0.39) | CTSSCTSKTP53 | |
| SCHEMBL13316632 | 0.71 | KDM4C (0.36) | ALOX5APFEN1 | |
| SCHEMBL21656172 | 0.71 | PRSS1 (0.39) | CTSSCTSKCTSL | |
| SCHEMBL30502337 | 0.69 | CTSS (0.40) | CTSSCTSKCTSL | |
| SCHEMBL13316668 | 0.68 | S1PR3 (0.39) | CNR2CTSSCTSKCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7745459-B2 | Quinolizinone compound and use thereof as HIV integrase inhibitor | JAPAN TOBACCO INC. (JP) | 2010-06-29 | — | — | US | disclosed |
| US-7745459-B2 | Quinolizinone compound and use thereof as HIV integrase inhibitor | JAPAN TOBACCO INC. (JP) | 2010-06-29 | — | — | US | disclosed |