Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 11/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8662724 | 0.75 | GPR35 (0.46) | GPR35CYP19A1ALDH1A1TP53HPGD | |
| SCHEMBL10876009 | 0.75 | ALDH1A1 (0.63) | GPR35ALDH1A1TP53HPGDTSHR | |
| SCHEMBL2122702 | 0.73 | CYP19A1 (0.48) | CYP19A1ALDH1A1HTT | |
| SCHEMBL594453 | 0.71 | ALDH1A1 (0.55) | CYP19A1ALDH1A1TSHRSMN1; SMN2L3MBTL1 | |
| SCHEMBL13514349 | 0.71 | CYP19A1 (0.56) | CYP19A1ALDH1A1HTT | |
| SCHEMBL31738343 | 0.70 | GPR35 (0.55) | GPR35ALDH1A1TP53HPGDTSHR | |
| SCHEMBL30204314 | 0.70 | CYP19A1 (0.45) | CYP19A1ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL9022132 | 0.70 | HSD17B10 (0.53) | CYP19A1ALDH1A1SMN1; SMN2 | |
| SCHEMBL1678369 | 0.70 | GPR35 (0.50) | GPR35CYP19A1ALDH1A1TP53HPGD | |
| SCHEMBL9488095 | 0.69 | PTGS2 (0.41) | GPR35CYP19A1ALDH1A1TP53L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7741520-B2 | Sulfonanilide analogs as selective aromatase modulators (SAMs) | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2010-06-22 | — | — | US | disclosed |
| US-20080045598-A1 | Novel sulfonanilide analogs as selective aromatase modulators (SAMs) | THE OHIO STATE UNIVERSITY (US) | 2008-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080045598-A1 | Novel sulfonanilide analogs as selective aromatase modulators (SAMs) | CYP19A1, AR, SULT2A1 | GPR35 512/4885CYP19A1 1/4885ALDH1A1 122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.