SCHEMBL133186

SCHEMBL133186

SCCCCc1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.58
MAOB P27338 2/20 0.56
SIGMAR1 Q99720 8/20 0.56
L3MBTL1 Q9Y468 1/20 0.52
IDO1 P14902 1/20 0.50
MAPT P10636 1/20 0.50
RXFP1 Q9HBX9 1/20 0.50
HTR2A P28223 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13606188 0.97 SIGMAR1 (0.59) MAOAMAOBSIGMAR1L3MBTL1MAPT
SCHEMBL128294 0.97 SIGMAR1 (0.59) MAOAMAOBSIGMAR1L3MBTL1MAPT
SCHEMBL13606187 0.97 SIGMAR1 (0.59) MAOAMAOBSIGMAR1L3MBTL1MAPT
SCHEMBL11510150 0.97 SIGMAR1 (0.59) MAOAMAOBSIGMAR1L3MBTL1MAPT
SCHEMBL15105362 0.97 SIGMAR1 (0.59) MAOAMAOBSIGMAR1L3MBTL1MAPT
SCHEMBL15105416 0.97 SIGMAR1 (0.59) MAOAMAOBSIGMAR1L3MBTL1MAPT
SCHEMBL13606194 0.97 SIGMAR1 (0.59) MAOAMAOBSIGMAR1L3MBTL1MAPT
SCHEMBL9998889 0.97 SIGMAR1 (0.59) MAOAMAOBSIGMAR1L3MBTL1MAPT
SCHEMBL7646991 0.97 SIGMAR1 (0.59) MAOAMAOBSIGMAR1L3MBTL1MAPT
SCHEMBL13606190 0.97 SIGMAR1 (0.59) MAOAMAOBSIGMAR1L3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 398 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119877273-A Carbon fiber sizing agent matched with (poly) dicyclopentadiene and application thereof 吉林大学 2025-04-25 CN disclosed
US-20240116075-A1 SUBSTRATE, SELECTIVE FILM DEPOSITION METHOD, DEPOSITION FILM OF ORGANIC MATTER, AND ORGANIC MATTER CENTRAL GLASS COMPANY, LIMITED (JP) 2024-04-11 US disclosed
CN-113149883-B Process for preparing pyrrole compounds 武田药品工业株式会社 2024-04-02 CN disclosed
EP-4287240-A1 SUBSTRATE, SELECTIVE FILM DEPOSITION METHOD, DEPOSITION FILM OF ORGANIC MATTER, AND ORGANIC MATTER Central Glass Company, Limited (JP) 2023-12-06 EP disclosed
US-20230322669-A1 METHOD FOR PRODUCING PYRROLE COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2023-10-12 US disclosed
EP-4257577-A2 METHOD FOR PRODUCING PYRROLE COMPOUND Takeda Pharmaceutical Company Limited (JP) 2023-10-11 EP disclosed
US-11649206-B2 Method for producing pyrrole compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2023-05-16 US disclosed
US-20230143246-A1 LIQUID PREPARATIONS OF AMINES AND ORGANIC ACIDS STABILIZED BY SALTS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2023-05-11 US disclosed
US-20230088365-A1 PROCESS FOR PRODUCING PYRROLE COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2023-03-23 US disclosed
US-20220411449-A1 Method for Preparing Heteroleptic Triarylbismuthanes and Compounds Produced by the Same UNIVERSITY OF HAWAII 2022-12-29 US disclosed
EP-0480052-A1 QUINOLINE DERIVATIVE, ANTIULCER DRUG CONTAINING THE SAME, AND PRODUCTION OF SAID DERIVATIVE OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1992-04-15 EP disclosed
US-4576753-A MICROBIOCIDES, ANTIBIOTICS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1986-03-18 US disclosed
US-4478833-A ANTICOAGULANTS DR. KARL THOMAE GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1984-10-23 US disclosed
US-4472300-A ANTIMICROBIAL FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1984-09-18 US disclosed
US-4472309-A ANTIMICROBIAL FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1984-09-18 US disclosed
US-4304718-A ANTIBIOTICS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1981-12-08 US disclosed
US-4218309-A HEAT TREATMENT OF PRODUCT FROM IN SITU RETORTING OF OIL SHALE OCCIDENTAL RESEARCH CORPORATION (US) 1980-08-19 US disclosed
US-4207234-A 4-Unsubstituted azetidinone derivatives and process for preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1980-06-10 US disclosed
US-4181800-A ANTIBIOTICS FROM SUBSTITUTED PERHYDRO-S-TRIAZINES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1980-01-01 US disclosed
US-3956345-A POLYESTER CIBA-GEIGY AG (CH) 1976-05-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220411449-A1 Method for Preparing Heteroleptic Triarylbismuthanes and Compounds Produced by the Same COASY, HAGH, MRM1 MAOA 373/4885MAOB 356/4885SIGMAR1 2160/4885
US-20230088365-A1 PROCESS FOR PRODUCING PYRROLE COMPOUND DHPS, STS, HPD MAOA 605/4885MAOB 500/4885SIGMAR1 3270/4885
US-20230143246-A1 LIQUID PREPARATIONS OF AMINES AND ORGANIC ACIDS STABILIZED BY SALTS OTC, SLC38A7, SRI MAOA 4/4885MAOB 8/4885SIGMAR1 248/4885
US-20230322669-A1 METHOD FOR PRODUCING PYRROLE COMPOUND HPD, PPOX, CBR3 MAOA 231/4885MAOB 234/4885SIGMAR1 3736/4885
US-11649206-B2 Method for producing pyrrole compound HPD, PPOX, CBR3 MAOA 231/4885MAOB 234/4885SIGMAR1 3736/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.