Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.73 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | GALR3 | O60755 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL171840 | 0.85 | MEN1 (0.61) | HDAC1MEN1KMT2AHPGDMAPT | |
| SCHEMBL11872758 | 0.83 | ALDH1A1 (0.63) | HDAC1MEN1KMT2AHPGDMAPT | |
| SCHEMBL8290704 | 0.82 | ALDH1A1 (0.61) | MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL7511572 | 0.81 | MEN1 (0.88) | MEN1KMT2AHPGDMAPTHTT | |
| SCHEMBL19002729 | 0.81 | RAB9A (0.69) | HDAC1MEN1KMT2AHPGDMAPT | |
| SCHEMBL14410496 | 0.81 | MEN1 (0.58) | HDAC1MEN1KMT2AHPGDMAPT | |
| SCHEMBL31504023 | 0.81 | MEN1 (0.88) | MEN1KMT2AHPGDMAPTHTT | |
| SCHEMBL19275848 | 0.81 | HDAC1 (0.51) | HDAC1MEN1KMT2AALDH1A1 | |
| SCHEMBL1255820 | 0.81 | ATF4 (0.63) | MEN1KMT2AALDH1A1 | |
| SCHEMBL1257639 | 0.81 | LMNA (0.63) | MEN1KMT2AHPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180019402-A1 | FORMATION OF CARBON NANOTUBE-CONTAINING DEVICES | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2018-01-18 | — | — | US | disclosed |
| US-7727505-B2 | Methods for separating carbon nanotubes by enhancing the density differential | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2010-06-01 | — | — | US | disclosed |
| US-20100041653-A1 | COMPOSITION AND METHODS FOR THE DESIGN AND DEVELOPMENT OF METALLO-ENZYME INHIBITORS | BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2010-02-18 | — | — | US | disclosed |
| US-20100041653-A1 | COMPOSITION AND METHODS FOR THE DESIGN AND DEVELOPMENT OF METALLO-ENZYME INHIBITORS | BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2010-02-18 | — | — | US | disclosed |
| US-20090291041-A1 | METHODS FOR SEPERATING CARBON NANOTUBES BY ENHANCING THE DENSITY DIFFERENTIAL | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2009-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041653-A1 | COMPOSITION AND METHODS FOR THE DESIGN AND DEVELOPMENT OF METALLO-ENZYME INHIBITORS | HELZ, MMEL1, GAA | HDAC1 28/4885MEN1 3212/4885KMT2A 764/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.