Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.49 |
| ▸ | RAB9A | P51151 | 12/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 12/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.49 |
| ▸ | NPC1 | O15118 | 10/20 | 0.49 |
| ▸ | HPGD | P15428 | 9/20 | 0.49 |
| ▸ | TP53 | P04637 | 9/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.49 |
| ▸ | CASP3 | P42574 | 4/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 4/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 4/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.46 |
| ▸ | RELA | Q04206 | 4/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29723524 | 1.00 | KDM4E (0.49) | KDM4ERAB9ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL3291037 | 0.87 | ALOX5 (0.55) | KDM4ERAB9ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL13327382 | 0.81 | MAPT (0.53) | KDM4ERAB9ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL13327367 | 0.78 | MAPT (0.43) | KDM4ERAB9ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL13327380 | 0.77 | RAB9A (0.38) | KDM4ERAB9ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL13327377 | 0.74 | RAB9A (0.42) | KDM4ERAB9ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL28380716 | 0.74 | KDM4E (0.45) | KDM4ERAB9ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL10045379 | 0.72 | KDM4E (0.53) | KDM4ERAB9ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL804301 | 0.71 | KDM6B (0.50) | KDM4ERAB9ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL14947173 | 0.70 | ALDH1A1 (0.96) | KDM4ERAB9ASMN1; SMN2ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1838682-B1 | COMPOUNDS THAT ABSORB ULTRAVIOLET LIGHT, METHODS OF THEIR PREPARATION AND OPTICAL LENSES CONTAINING THEM | ESSILOR INT (FR) | 2013-09-25 | — | — | EP | claimed |
| US-7713452-B2 | Compounds that absorb ultraviolet light, methods of their preparation and optical lenses containing them | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) | 2010-05-11 | — | — | US | claimed |
| US-20080064880-A1 | Compounds That Absorb Ultraviolet Light, Methods of Their Preparation and Optical Lenses Containing Them | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D' OPTIQUE (FR) | 2008-03-13 | — | — | US | claimed |
| EP-1838682-A2 | COMPOUNDS THAT ABSORB ULTRAVIOLET LIGHT, METHODS OF THEIR PREPARATION AND OPTICAL LENSES CONTAINING THEM | ESSILOR INTERNATIONAL Compagnie Générale d'Optique (FR) | 2007-10-03 | — | — | EP | claimed |
| WO-2006069811-A2 | COMPOUNDS THAT ABSORB ULTRAVIOLET LIGHT, METHODS OF THEIR PREPARATION AND OPTICAL LENSES CONTAINING THEM | ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) | 2006-07-06 | — | — | WO | claimed |
| EP-4530054-A1 | OPTICAL ARTICLE COMPRISING A SUBSTRATE FOR MYOPIA CONTROL WITH EMBEDDED NANOPARTICLES | Essilor International (FR) | 2025-04-02 | — | — | EP | disclosed |
| EP-3665514-B1 | OPTICAL ARTICLE COMPRISING A SUBSTRATE WITH EMBEDDED PARTICLES FOR LIGHT TRANSMISSION ENHANCEMENT | ESSILOR INT (FR) | 2024-10-02 | — | — | EP | disclosed |
| EP-3632950-B1 | STORAGE-STABLE HEAT-CURABLE HYBRID EPOXY FUNCTIONAL COMPOSITION AND TRANSPARENT HEAT-CURED COATINGS PREPARED THEREFROM | ESSILOR INT (FR) | 2024-07-17 | — | — | EP | disclosed |
| EP-3665515-B1 | OPTICAL ARTICLE COMPRISING A SUBSTRATE WITH EMBEDDED PARTICLES FOR ABRASION AND/OR SCRATCH RESISTANCE ENHANCEMENT | ESSILOR INT (FR) | 2024-01-17 | — | — | EP | disclosed |
| US-11852784-B2 | Optical article comprising a substrate with embedded particles for light transmission enhancement | ESSILOR INTERNATIONAL (FR) | 2023-12-26 | — | — | US | disclosed |
| EP-3327091-B1 | EPOXY FUNCTIONAL COMPOSITION PROTECTING DYES FROM PHOTO-DEGRADATION AND CURED COATINGS PREPARED THEREFROM | ESSILOR INT (FR) | 2023-01-18 | — | — | EP | disclosed |
| EP-3318920-B1 | NEAR INFRARED LIGHT-CUTTING OPTICAL ARTICLES WITH LOW RESIDUAL COLOR | ESSILOR INT (FR) | 2022-07-06 | — | — | EP | disclosed |
| US-7713452-B2 | Compounds that absorb ultraviolet light, methods of their preparation and optical lenses containing them | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) | 2010-05-11 | — | — | US | disclosed |
| US-7713452-B2 | Compounds that absorb ultraviolet light, methods of their preparation and optical lenses containing them | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) | 2010-05-11 | — | — | US | disclosed |
| US-7713452-B2 | Compounds that absorb ultraviolet light, methods of their preparation and optical lenses containing them | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) | 2010-05-11 | — | — | US | disclosed |
| US-20080064880-A1 | Compounds That Absorb Ultraviolet Light, Methods of Their Preparation and Optical Lenses Containing Them | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D' OPTIQUE (FR) | 2008-03-13 | — | — | US | disclosed |
| US-20080064880-A1 | Compounds That Absorb Ultraviolet Light, Methods of Their Preparation and Optical Lenses Containing Them | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D' OPTIQUE (FR) | 2008-03-13 | — | — | US | disclosed |
| US-20080064880-A1 | Compounds That Absorb Ultraviolet Light, Methods of Their Preparation and Optical Lenses Containing Them | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D' OPTIQUE (FR) | 2008-03-13 | — | — | US | disclosed |
| EP-1838682-A2 | COMPOUNDS THAT ABSORB ULTRAVIOLET LIGHT, METHODS OF THEIR PREPARATION AND OPTICAL LENSES CONTAINING THEM | ESSILOR INTERNATIONAL Compagnie Générale d'Optique (FR) | 2007-10-03 | — | — | EP | disclosed |
| WO-2006069811-A2 | COMPOUNDS THAT ABSORB ULTRAVIOLET LIGHT, METHODS OF THEIR PREPARATION AND OPTICAL LENSES CONTAINING THEM | ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) | 2006-07-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080064880-A1 | Compounds That Absorb Ultraviolet Light, Methods of Their Preparation and Optical Lenses Containing Them | CRYAB, CRYAA, CRYZ | KDM4E 805/4885RAB9A 2410/4885SMN1; SMN2 4736/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.