Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPD | P32754 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.40 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13751933 | 0.83 | HPD (0.67) | HPDMAPTMEN1PKMKMT2A | |
| SCHEMBL9191354 | 0.83 | HPD (0.67) | HPDCYP3A4ALDH1A1MEN1PKM | |
| SCHEMBL9711707 | 0.83 | HPD (0.48) | HPDTSHRCYP3A4ALDH1A1MAPT | |
| Mesotrione SCHEMBL4895947 | 0.83 | HPD (0.62) | HPDALDH1A1MAPTMEN1LMNA | |
| Mesotrione SCHEMBL22116 | 0.83 | HPD (0.62) | HPDALDH1A1MAPTMEN1LMNA | |
| SCHEMBL19295182 | 0.83 | HPD (0.62) | HPDMAPTMEN1PKMKMT2A | |
| Mesotrione SCHEMBL29352201 | 0.83 | HPD (0.62) | HPDALDH1A1MAPTMEN1LMNA | |
| Mesotrione SCHEMBL2233142 | 0.82 | HPD (0.61) | HPDALDH1A1MAPTMEN1LMNA | |
| Mesotrione SCHEMBL20723476 | 0.82 | HPD (0.61) | HPDALDH1A1MAPTMEN1LMNA | |
| Mesotrione SCHEMBL1667345 | 0.82 | HPD (0.61) | HPDALDH1A1MAPTMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160324785-A1 | Pharmaceutical Composition | CYCLE PHARMACEUTICALS LTD. (GB) | 2016-11-10 | — | — | US | disclosed |
| US-20140162880-A1 | Controlled Release Granules | SYNGENTA CROP PROTECTION, INC. (US) | 2014-06-12 | — | — | US | disclosed |
| US-8748343-B2 | Herbicide/safener combintions | BAYER CROPSCIENCE AG (DE) | 2014-06-10 | — | — | US | disclosed |
| US-20120322657-A1 | HERBICIDE/SAFENER COMBINTIONS | ZIEMER FRANK (DE) | 2012-12-20 | — | — | US | disclosed |
| US-20100113269-A1 | CONTROLLED RELEASE GRANULES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120322657-A1 | HERBICIDE/SAFENER COMBINTIONS | DDT, DERL1, SLC16A7 | HPD 1093/4885TSHR 575/4885CYP3A4 906/4885 |
| US-20100113269-A1 | CONTROLLED RELEASE GRANULES | NSF, SLC18A1, GET3 | HPD 1519/4885TSHR 3176/4885CYP3A4 2258/4885 |
| US-20140162880-A1 | Controlled Release Granules | NSF, SLC18A1, GET3 | HPD 1519/4885TSHR 3176/4885CYP3A4 2258/4885 |
| US-20160324785-A1 | Pharmaceutical Composition | TPH1, HTT, NAT1 | HPD 258/4885TSHR 3059/4885CYP3A4 652/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.