SCHEMBL1333756

SCHEMBL1333756

Cc1cc(C)c(N)c(CS)c1N

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.43
CYP3A4 P08684 2/20 0.43
TSHR P16473 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
TP53 P04637 1/20 0.43
MAPK1 P28482 1/20 0.38
POLB P06746 1/20 0.37
MAPT P10636 1/20 0.32
NOS3 P29474 3/20 0.31
NOS2 P35228 3/20 0.31
KDM4E B2RXH2 1/20 0.31
NOS1 P29475 1/20 0.31
CYP1A2 P05177 1/20 0.31
ALOX15 P16050 1/20 0.31
CASP7 P55210 1/20 0.31
HIF1A Q16665 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL261835 0.86 ALDH1A1 (0.37) ALDH1A1CYP3A4TSHRTDP1TP53
SCHEMBL1334762 0.83 ALDH1A1 (0.42) ALDH1A1CYP3A4TSHRTDP1TP53
SCHEMBL28244575 0.80 CYP3A4 (0.40) ALDH1A1CYP3A4TSHRTDP1TP53
SCHEMBL2724396 0.80 NOS2 (0.37) ALDH1A1CYP3A4TSHRTDP1TP53
SCHEMBL28858266 0.78 SLC11A2 (0.34) ALDH1A1CYP3A4TSHRTDP1TP53
SCHEMBL342202 0.76 ALDH1A1 (0.46) ALDH1A1CYP3A4TSHRTDP1TP53
SCHEMBL5609755 0.74 TDP1 (0.50) ALDH1A1CYP3A4TSHRTDP1TP53
SCHEMBL1334951 0.73 NOS3 (0.37) ALDH1A1CYP3A4TSHRTDP1TP53
SCHEMBL5352095 0.72 IDO1 (0.38) TDP1MAPT
SCHEMBL441710 0.72 PGK1 (0.44) TDP1MAPTHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1504869-B1 PROCESS FOR PRODUCING OPTICAL MEMBER, PROCESS FOR PRODUCING PLASTIC LENS, GASKET FOR PLASTIC LENS MOLDING, AND JIG FOR MONOMER INJECTION HOYA CORP (JP) 2018-03-28 EP disclosed
EP-2351638-B1 PLASTIC LENS MANUFACTURING METHOD AND MANUFACTURING DEVICE HOYA CORP (JP) 2016-11-23 EP disclosed
EP-1759824-B1 METHOD OF MANUFACTURING PLASTIC LENSES HOYA CORP (JP) 2016-03-09 EP disclosed
US-20150259509-A1 TRANSPARENT MOLDED ARTICLE, OPTICAL MEMBER, PLASTIC LENS, AND METHODS OF MANUFACTURING SAME HOYA CORPORATION (JP) 2015-09-17 US disclosed
CN-101648421-B Method of manufacturing plastic lens, gasket for molding plastic lens, casting mold for molding plastic lens, casting jig for plastic lens starting material liquid, holding member for plastic lens cas HOYA CORPORATION (JP) 2014-10-15 CN disclosed
US-8377345-B2 Method of manufacturing optical member, method of manufacturing plastic lens, gasket for molding plastic lens, and jog for casting monomer HOYA CORPORATION (JP) 2013-02-19 US disclosed
US-8372317-B2 Method of casting plastic lens starting material liquid and casting apparatus and method of manufacturing plastic lens HOYA CORPORATION (JP) 2013-02-12 US disclosed
US-20110278747-A1 MANUFACTURING METHOD AND MANUFACTURING APPARATUS OF PLASTIC LENS HOYA CORPORATION (JP) 2011-11-17 US disclosed
EP-2351638-A1 PLASTIC LENS MANUFACTURING METHOD AND MANUFACTURING DEVICE Hoya Corporation (JP) 2011-08-03 EP disclosed
US-7919020-B2 Method of manufacturing plastic lens, gasket for molding plastic lens, casting mold for molding plastic lens, casting jig for plastic lens starting material liquid, holding member for plastic lens casting mold, and plastic lens manufacturing apparatus HOYA CORPORATION (JP) 2011-04-05 US disclosed
US-20100032852-A1 METHOD OF CASTING PLASTIC LENS STARTING MATERIAL LIQUID AND CASTING APPARATUS, AND METHOD OF MANUFACTURING PLASTIC LENS HOYA CORPORATION (JP) 2010-02-11 US disclosed
EP-2133187-A1 METHOD AND DEVICE FOR POURING PLASTIC LENS MATERIAL LIQUID AND METHOD OF PRODUCING PLASTIC LENS Hoya Corporation (JP) 2009-12-16 EP disclosed
EP-1384736-B1 TRANSPARENT MOLDED OBJECTS, OPTICAL MEMBER, PLASTIC LENS, AND PROCESSES FOR PRODUCING THESE HOYA CORP (JP) 2009-08-12 EP disclosed
US-20080029914-A1 Method of manufacturing plastic lens, gasket for molding plastic lens, casting mold for molding plastic lens, casting jig for plastic lens starting material liquid, holding member for plastic lens casting mold, and plastic lens manufacturing apparatus HOYA CORPORATION (JP) 2008-02-07 US disclosed
US-20080018005-A1 Method Of Manufacturing Plastic Lens, Gasket For Molding Plastic Lens, Casting Mold For Molding Plastic Lens, Casting Jig For Plastic Lens Starting Material Liquid, Holding Member For Plastic Lens Casting Mold, And Plastic Lens Manufacturing Apparatus HOYA CORPORATION 2008-01-24 US disclosed
EP-1759824-A1 PROCESSES FOR PRODUCTION OF PLASTIC LENSES, GASKET FOR MOLDING PLASTIC LENSES, MOLDS FOR MOLDING PLASTIC LENSES, INJECTION JIG FOR THE RAW MATERIAL FLUID OF PLASTIC LENSES, HOLDING FIXTURE FOR THE MOLDS FOR PLASTIC LENSES, AND PRODUCTION UNIT FOR PLASTIC LENSES HOYA CORPORATION (JP) 2007-03-07 EP disclosed
US-20060155093-A1 Polyol compound, transparent molded article and method of manufacturing transparent molded article HOYA CORPORATION (JP) 2006-07-13 US disclosed
EP-1640394-A1 POLYOL COMPOUND, TRANSPARENT MOLDED OBJECTS, AND PROCESS FOR PRODUCING TRANSPARENT MOLDED OBJECT HOYA CORPORATION (JP) 2006-03-29 EP disclosed
US-20050200033-A1 Process for producing optical member, process for producing plastic lens, gasket for plastic lens molding, and jig for monomer injection HOYA CORPORATION (JP) 2005-09-15 US disclosed
EP-1504869-A1 PROCESS FOR PRODUCING OPTICAL MEMBER, PROCESS FOR PRODUCING PLASTIC LENS, GASKET FOR PLASTIC LENS MOLDING, AND JIG FOR MONOMER INJECTION HOYA CORPORATION (JP) 2005-02-09 EP disclosed