Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.64 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.64 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.64 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.50 |
| ▸ | NPY1R | P25929 | 6/20 | 0.48 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | NOS2 | P35228 | 1/20 | 0.45 |
| ▸ | FURIN | P09958 | 5/20 | 0.43 |
| ▸ | PCSK6 | P29122 | 1/20 | 0.43 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.42 |
| ▸ | NPY4R | P50391 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29546257 | 1.00 | CHRM2 (0.64) | CHRM2CHRM4CHRM1CA1CA2 | |
| SCHEMBL29393341 | 0.86 | SIRT5 (0.64) | CHRM2CHRM4CHRM1CA1CA2 | |
| SCHEMBL14117893 | 0.85 | CHRM2 (0.69) | CHRM2CHRM4CHRM1CA1CA2 | |
| SCHEMBL16748402 | 0.83 | CHRM2 (0.68) | CHRM2CHRM4CHRM1CA1CA2 | |
| SCHEMBL29521677 | 0.83 | CHRM2 (0.68) | CHRM2CHRM4CHRM1CA1CA2 | |
| Water SCHEMBL30600465 | 0.82 | CHRM2 (0.66) | CHRM2CHRM4CHRM1CA1CA2 | |
| SCHEMBL22493159 | 0.81 | BMP1 (0.47) | CHRM2CHRM4CHRM1CA1CA2 | |
| SCHEMBL13698293 | 0.80 | SIRT6 (0.55) | CHRM2CHRM4CHRM1CA1CA2 | |
| SCHEMBL30080701 | 0.79 | CHRM2 (0.58) | CHRM2CHRM4CHRM1CA1CA2 | |
| SCHEMBL29595648 | 0.79 | FURIN (0.56) | CHRM2CHRM4CHRM1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100121105-A1 | Composition and Method of synthesizing a biomolecule and its therapeutics applications | BAKHTIARI MEHDI | 2010-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100121105-A1 | Composition and Method of synthesizing a biomolecule and its therapeutics applications | GHRHR, GHSR, IGF1R | CHRM2 3209/4885CHRM4 3790/4885CHRM1 3128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.