SCHEMBL30080701

SCHEMBL30080701

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nearest known ligand 0.58

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ CHRM2 P08172 1/20 0.58
▸ CHRM4 P08173 1/20 0.58
▸ CHRM1 P11229 1/20 0.58
▸ SIRT5 Q9NXA8 2/20 0.55
▸ FURIN P09958 9/20 0.52
▸ SIRT2 Q8IXJ6 1/20 0.52
▸ NPY1R P25929 3/20 0.47
▸ NPY5R Q15761 2/20 0.47
▸ CA1 P00915 2/20 0.46
▸ CA2 P00918 2/20 0.46
▸ F2 P00734 1/20 0.44
▸ NRP1 O14786 1/20 0.43
▸ NPY4R P50391 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29595648 0.91 FURIN (0.56) CHRM2CHRM4CHRM1SIRT5FURIN
SCHEMBL29393341 0.90 SIRT5 (0.64) CHRM2CHRM4CHRM1SIRT5FURIN
SCHEMBL14117893 0.89 CHRM2 (0.69) CHRM2CHRM4CHRM1SIRT5NPY1R
Etelcalcetide SCHEMBL29647613 0.81 SIRT5 (0.49) CHRM2CHRM4CHRM1SIRT5FURIN
Trifluoroacetic Acid SCHEMBL31741398 0.81 SIRT5 (0.59) CHRM2CHRM4CHRM1SIRT5FURIN
SCHEMBL20548856 0.81 SIRT5 (0.53) CHRM2CHRM4CHRM1SIRT5FURIN
Etelcalcetide SCHEMBL30221949 0.81 SIRT5 (0.48) CHRM2CHRM4CHRM1SIRT5FURIN
SCHEMBL13337947 0.79 CHRM2 (0.64) CHRM2CHRM4CHRM1SIRT5FURIN
SCHEMBL29546257 0.79 CHRM2 (0.64) CHRM2CHRM4CHRM1SIRT5FURIN
SCHEMBL16748402 0.79 CHRM2 (0.68) CHRM2CHRM4CHRM1SIRT5CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250361280-A1 CONJUGATED HEPCIDIN MIMETICS PROTAGONIST THERAPEUTICS INC (US) 2025-11-27 — — US disclosed
US-20250320471-A1 Method for Producing Compounds, Method for Producing Compound Library, Compound Library, and Screening Method UNIV TOKYO (JP) 2025-10-16 — — US disclosed
EP-4431519-A1 METHOD FOR PRODUCING COMPOUNDS, METHOD FOR PRODUCING COMPOUND LIBRARY, COMPOUND LIBRARY, AND SCREENING METHOD The University of Tokyo (JP) 2024-09-18 — — EP disclosed
CN-118451088-A Method for producing compound, method for producing compound library, and screening method 国立大学法人东京大学 2024-08-06 — — CN disclosed
EP-4353248-A1 CALCIUM-SENSING RECEPTOR AGONIST COMPOSITION AND APPLICATION THEREOF Beijing Tuo Jie Biopharmaceutical Co. Ltd. (CN) 2024-04-17 — — EP disclosed
US-20240094161-A1 THIN FILM, BIOSENSOR, AND METHOD FOR PRODUCING THEM THE UNIVERSITY OF TOKYO (JP) 2024-03-21 — — US disclosed
CN-117500820-A Hydrochloride of calcium sensitive receptor agonist compound, pharmaceutical composition and application thereof 北京拓界生物医药科技有限公司 2024-02-02 — — CN disclosed
CN-117295510-A Composition of calcium sensitive receptor agonist and application thereof 北京拓界生物医药科技有限公司 2023-12-26 — — CN disclosed
EP-4280287-A1 THIN FILM, BIOSENSOR, AND METHOD FOR MANUFACTURING SAME The University of Tokyo (JP) 2023-11-22 — — EP disclosed
CN-116745607-A Thin film, biosensor, and method for producing the same 国立大学法人东京大学 2023-09-12 — — CN disclosed
WO-2023068296-A1 METHOD FOR PRODUCING COMPOUNDS, METHOD FOR PRODUCING COMPOUND LIBRARY, COMPOUND LIBRARY, AND SCREENING METHOD 国立大学法人東京大学 2023-04-27 — — WO disclosed
US-20230041996-A1 CALCIUM-SENSING RECEPTOR AGONIST COMPOUND AND APPLICATION THEREOF BEIJING TUO JIE BIOPHARMACEUTICAL CO. LTD. (CN) 2023-02-09 — — US disclosed
WO-2022257958-A1 CALCIUM-SENSING RECEPTOR AGONIST COMPOSITION AND APPLICATION THEREOF 北京拓界生物医药科技有限公司 2022-12-15 — — WO disclosed
WO-2022257940-A1 HYDROCHLORIDE SALT OF CALCIUM-SENSING RECEPTOR AGONIST COMPOUND AND PHARMACEUTICAL COMPOSITION AND USE THEREOF 北京拓界生物医药科技有限公司 2022-12-15 — — WO disclosed
EP-4091623-A1 CALCIUM-SENSING RECEPTOR AGONIST COMPOUND AND APPLICATION THEREOF Beijing Tuo Jie Biopharmaceutical Co. Ltd. (CN) 2022-11-23 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250361280-A1 CONJUGATED HEPCIDIN MIMETICS HAMP, VIP, HDGF CHRM2 4836/4885CHRM4 4802/4885CHRM1 4812/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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