SCHEMBL25925637

SCHEMBL25925637

Bc1cc(C)cc(P)c1O

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SELL P14151 1/20 0.40
SELP P16109 1/20 0.40
SELE P16581 1/20 0.40
ALDH1A1 P00352 4/20 0.36
ACHE P22303 1/20 0.35
POLB P06746 2/20 0.34
CA2 P00918 1/20 0.34
TYR P14679 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
KDM4E B2RXH2 2/20 0.34
GAA P10253 2/20 0.34
MAPT P10636 2/20 0.34
APEX1 P27695 1/20 0.34
MPI P34949 1/20 0.34
RECQL P46063 1/20 0.34
KMT2A Q03164 1/20 0.34
LMNA P02545 1/20 0.33
ERN1 O75460 1/20 0.33
GPR35 Q9HC97 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13342004 0.82 SELL (0.50) SELLSELPSELEALDH1A1ACHE
SCHEMBL14016309 0.75 ALDH1A1 (0.52) SELLSELPSELEALDH1A1ACHE
SCHEMBL14392219 0.71 CA2 (0.42) SELLSELPSELEALDH1A1ACHE
SCHEMBL13772784 0.68 AMY1A (0.38) SELLSELPSELEALDH1A1ACHE
SCHEMBL3554507 0.67 ERN1 (0.72) SELLSELPSELEERN1
SCHEMBL3524436 0.64 GLA (0.46) SELLSELPSELEALDH1A1GAA
SCHEMBL23080309 0.64 ACHE (0.37) SELLSELPSELEALDH1A1ACHE
SCHEMBL20682673 0.64 ALDH1A1 (0.37) SELLSELPSELEALDH1A1ACHE
SCHEMBL16449520 0.64 ALDH1A1 (0.37) SELLSELPSELEALDH1A1ACHE
SCHEMBL25707683 0.64 ACHE (0.40) SELLSELPSELEALDH1A1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230242492-A1 THYROMIMETICS AUTOBAHN THERAPEUTICS, INC. 2023-08-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230242492-A1 THYROMIMETICS TPO, TSHR, THOP1 SELL 4856/4885SELP 4757/4885SELE 4310/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.