Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 6/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1332108 | 0.86 | KCNH2 (0.53) | KCNH2 | |
| SCHEMBL13149418 | 0.82 | EPHX2 (0.60) | L3MBTL1KDM4EALDH1A1LMNAGAA | |
| SCHEMBL7032539 | 0.82 | LTA4H (0.57) | LTA4HKCNA5KCNH2 | |
| SCHEMBL1334001 | 0.82 | KCNH2 (0.52) | LTA4HPTGS2L3MBTL1DRD2KCNA5 | |
| Hydrochloric Acid SCHEMBL1332047 | 0.81 | KCNH2 (0.57) | LTA4HKCNH2 | |
| Hydrochloric Acid SCHEMBL1332883 | 0.81 | KCNH2 (0.54) | LTA4HPTGS2L3MBTL1DRD2KCNA5 | |
| SCHEMBL7134913 | 0.80 | LTA4H (0.69) | LTA4HPTGS2KCNH2HTTKMT2A | |
| SCHEMBL14776017 | 0.79 | KCNA3 (0.50) | KCNH2GAA | |
| SCHEMBL13149633 | 0.79 | KDM4E (0.78) | KDM4EALDH1A1ATMGAAHTT | |
| SCHEMBL1332740 | 0.78 | L3MBTL1 (0.65) | LTA4HL3MBTL1DRD2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130072497-A1 | N- SUBSTITUTED PIPERAZINES | DOW AGROSCIENCES LLC (US) | 2013-03-21 | — | — | US | disclosed |
| US-20130072497-A1 | N- SUBSTITUTED PIPERAZINES | DOW AGROSCIENCES LLC (US) | 2013-03-21 | — | — | US | disclosed |
| US-8338430-B2 | N-substituted piperazines | DOW AGROSCIENCES, LLC. (US) | 2012-12-25 | — | — | US | disclosed |
| US-8338430-B2 | N-substituted piperazines | DOW AGROSCIENCES, LLC. (US) | 2012-12-25 | — | — | US | disclosed |
| CN-101511187-B | Piperidine and piperazine derivatives | MS SCIENCE CORP | 2012-07-04 | — | — | CN | disclosed |
| US-8183374-B2 | Piperidine and piperazine derivatives | M'S SCIENCE CORPORATION (JP) | 2012-05-22 | — | — | US | disclosed |
| US-20110281890-A1 | Piperidine and piperazine derivatives | M'S SCIENCE CORPORATION | 2011-11-17 | — | — | US | disclosed |
| EP-2340835-A1 | Piperidine and piperazine derivatives | M's Science Corporation (JP) | 2011-07-06 | — | — | EP | disclosed |
| EP-1976525-B1 | PIPERIDINE AND PIPERAZINE DERIVATIVES | MS SCIENCE CORP (JP) | 2010-11-03 | — | — | EP | disclosed |
| US-20100256162-A1 | Piperazine and Piperidine Derivatives | AGY THERAPEUTICS, INC. (US) | 2010-10-07 | — | — | US | disclosed |
| US-20100234391-A1 | N-SUBSTITUTED PIPERAZINES | DOW AGROSCIENCES LLC (US) | 2010-09-16 | — | — | US | disclosed |
| US-20100234391-A1 | N-SUBSTITUTED PIPERAZINES | DOW AGROSCIENCES LLC (US) | 2010-09-16 | — | — | US | disclosed |
| US-7754724-B2 | N-substituted piperazines | DOW AGROSCIENCES LLC (US) | 2010-07-13 | — | — | US | disclosed |
| US-7754724-B2 | N-substituted piperazines | DOW AGROSCIENCES LLC (US) | 2010-07-13 | — | — | US | disclosed |
| US-20100137334-A1 | Piperidine and Piperazine Derivatives | SUN CONNIE L | 2010-06-03 | — | — | US | disclosed |
| US-20070004750-A1 | N-substituted piperazines | CORTEVA AGRISCIENCE LLC | 2007-01-04 | — | — | US | disclosed |
| US-20070004750-A1 | N-substituted piperazines | CORTEVA AGRISCIENCE LLC | 2007-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070004750-A1 | N-substituted piperazines | PRXL2A, CNPY2, CYP4X1 | LTA4H 3316/4885PTGS2 2091/4885L3MBTL1 2862/4885 |
| US-20100234391-A1 | N-SUBSTITUTED PIPERAZINES | PRXL2A, CNPY2, CYP4X1 | LTA4H 3316/4885PTGS2 2091/4885L3MBTL1 2862/4885 |
| US-20100137334-A1 | Piperidine and Piperazine Derivatives | SIGMAR1, OPRM1, OPRD1 | LTA4H 2934/4885PTGS2 1667/4885L3MBTL1 1911/4885 |
| US-20130072497-A1 | N- SUBSTITUTED PIPERAZINES | PRXL2A, CNPY2, CYP4X1 | LTA4H 3316/4885PTGS2 2091/4885L3MBTL1 2862/4885 |
| US-20110281890-A1 | Piperidine and piperazine derivatives | SIGMAR1, OPRM1, OPRD1 | LTA4H 3597/4885PTGS2 2050/4885L3MBTL1 1744/4885 |
| US-20100256162-A1 | Piperazine and Piperidine Derivatives | SIGMAR1, OPRM1, OPRD1 | LTA4H 3616/4885PTGS2 2008/4885L3MBTL1 1771/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.