Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 3/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6603564 | 0.90 | HDAC3 (0.46) | HDAC3HDAC1HDAC6ALDH1A1ACHE | |
| SCHEMBL13342907 | 0.86 | HDAC3 (0.41) | HDAC3HDAC1HDAC6ACKR3KDM4E | |
| SCHEMBL14076071 | 0.82 | ALDH1A1 (0.38) | ALDH1A1ACHEHPGDSKDM4E | |
| SCHEMBL3586130 | 0.81 | KDM4A (0.40) | KDM4EKDM4A | |
| SCHEMBL20691496 | 0.81 | HDAC3 (0.66) | HDAC3HDAC1HDAC6ALDH1A1ACHE | |
| SCHEMBL7097142 | 0.77 | ALDH1A1 (0.54) | HDAC3HDAC1HDAC6ALDH1A1HPGDS | |
| SCHEMBL1852466 | 0.76 | HDAC3 (0.52) | HDAC3HDAC1HDAC6ABCB1KDM4E | |
| SCHEMBL3595386 | 0.76 | ACHE (0.51) | HDAC3HDAC1HDAC6ALDH1A1ACHE | |
| SCHEMBL6605610 | 0.76 | KMT2A (0.42) | ACHEKDM4E | |
| SCHEMBL21191429 | 0.74 | CYP2C19 (0.41) | HDAC3HDAC1HDAC6ALDH1A1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100113305-A1 | OXAZOLE AND THIAZOLE COMBINATORIAL LIBRARIES | BOARD OF GOVERNORS FOR HIGHER EDUCATION, STATE OF RHODE ISLAND AND PROVIDENCE PLANTATIONS (US) | 2010-05-06 | — | — | US | disclosed |
| US-20100113305-A1 | OXAZOLE AND THIAZOLE COMBINATORIAL LIBRARIES | BOARD OF GOVERNORS FOR HIGHER EDUCATION, STATE OF RHODE ISLAND AND PROVIDENCE PLANTATIONS (US) | 2010-05-06 | — | — | US | disclosed |
| US-20080234132-A1 | Microcin B17 Analogs And Methods For Their Preparation And Use | PLANT BIOSCIENCE LIMITED (GB) | 2008-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080234132-A1 | Microcin B17 Analogs And Methods For Their Preparation And Use | MCM3, MCM7, CCNB3 | HDAC3 1204/4885HDAC1 1997/4885HDAC6 1851/4885 |
| US-20100113305-A1 | OXAZOLE AND THIAZOLE COMBINATORIAL LIBRARIES | OXA1L, SPOUT1, BCAT2 | HDAC3 854/4885HDAC1 988/4885HDAC6 418/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.