Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.49 |
| ▸ | CES1 | P23141 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | F7 | P08709 | 1/20 | 0.46 |
| ▸ | F3 | P13726 | 1/20 | 0.46 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.46 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25306337 | 0.86 | KMT2A (0.49) | KMT2AATMMAPK14GAAALDH1A1 | |
| SCHEMBL14060274 | 0.82 | ALDH1A1 (0.55) | GAAALDH1A1AGTR1OPRK1RAB9A | |
| SCHEMBL25308448 | 0.81 | MAPT (0.50) | KMT2AATMALDH1A1CYP1A1CYP1A2 | |
| SCHEMBL8801902 | 0.80 | LTA4H (0.61) | KMT2AMAPK14CES2CES1MEN1 | |
| SCHEMBL158348 | 0.80 | CES2 (0.59) | KMT2AATMMAPK14CES2CES1 | |
| SCHEMBL29765677 | 0.80 | CES2 (0.59) | KMT2AATMMAPK14CES2CES1 | |
| SCHEMBL30706504 | 0.79 | AGTR1 (0.57) | KMT2AATMCES2CES1GAA | |
| SCHEMBL10487079 | 0.79 | AGTR1 (0.57) | KMT2AATMCES2CES1GAA | |
| SCHEMBL30509806 | 0.78 | KMT2A (0.45) | KMT2AATMGAAALDH1A1APP | |
| SCHEMBL29691445 | 0.78 | LTA4H (0.63) | KMT2AATMGAAALDH1A1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010069882-A1 | ISOXAZOLE DERIVATIVES FOR USE AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-06-24 | — | — | WO | disclosed |
| WO-2010069881-A2 | ISOXAZOLE DERIVATIVES FOR USE AS PLANT GROWTH REGULATORS | SYNGENTA PARTICIPATIONS AG (CH) | 2010-06-24 | — | — | WO | disclosed |