Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 8/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | NQO1 | P15559 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 2/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12647196 | 0.82 | PGR (0.43) | PGRALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL14144031 | 0.73 | ALDH1A1 (0.50) | PGRALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL1408342 | 0.71 | MAPT (0.37) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL2719064 | 0.68 | ALDH1A1 (0.51) | PGRALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL24972224 | 0.68 | NR3C1 (0.54) | PGRNR3C1ARNR3C2 | |
| SCHEMBL3523036 | 0.67 | ALDH1A1 (0.60) | PGRALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL22291695 | 0.67 | MAPT (0.57) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL1408679 | 0.66 | MAPT (0.39) | ALDH1A1MAPTKDM4EHPGDNPSR1 | |
| SCHEMBL12809947 | 0.66 | ALDH1A1 (0.42) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL7989542 | 0.65 | MAPT (0.50) | ALDH1A1MAPTKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2186801-A2 | Intermediates for synthesizing dibenzorhodamine dyes | Applera Corporation (US) | 2010-05-19 | — | — | EP | disclosed |