Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NQO1 | P15559 | 1/20 | 0.39 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.39 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.36 |
| ▸ | KRAS | P01116 | 1/20 | 0.36 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.35 |
| ▸ | HNF4A | P41235 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12647199 | 0.80 | CYP1A2 (0.38) | MAPTALDH1A1MAPKAPK2NISCHSMN1; SMN2 | |
| SCHEMBL12809947 | 0.73 | ALDH1A1 (0.42) | MAPTALDH1A1NPSR1NQO1SMN1; SMN2 | |
| SCHEMBL1408900 | 0.71 | MAPT (0.39) | MAPTALDH1A1NPSR1NQO1SMN1; SMN2 | |
| SCHEMBL1408374 | 0.70 | MAPT (0.50) | MAPTALDH1A1NPSR1NQO1NISCH | |
| SCHEMBL1408738 | 0.68 | MEN1 (0.39) | MAPTALDH1A1NPSR1NQO1LMNA | |
| SCHEMBL12647693 | 0.68 | KDM4E (0.43) | MAPTALDH1A1NPSR1NQO1SMN1; SMN2 | |
| SCHEMBL12647417 | 0.68 | MAPT (0.55) | MAPTALDH1A1NPSR1NQO1NISCH | |
| SCHEMBL1128095 | 0.66 | NQO1 (0.56) | MAPTALDH1A1NPSR1NQO1SMN1; SMN2 | |
| SCHEMBL13352353 | 0.66 | PGR (0.42) | MAPTALDH1A1NPSR1NQO1HPGD | |
| SCHEMBL1506854 | 0.65 | POLB (0.42) | MAPTALDH1A1NISCHSMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1034221-B1 | DIBENZORHODAMINE DYES USEFUL AS FLUORESCENT LABELLING AGENTS | LIFE TECHNOLOGIES CORP (US) | 2014-05-14 | — | — | EP | disclosed |
| EP-1034221-B1 | DIBENZORHODAMINE DYES USEFUL AS FLUORESCENT LABELLING AGENTS | LIFE TECHNOLOGIES CORP (US) | 2014-05-14 | — | — | EP | disclosed |
| US-20110124510-A1 | METHODS OF LABELING POLYNUCLEOTIDE WITH DIBENZORHODAMINE DYES | Life Technologies Corporation (US) | 2011-05-26 | — | — | US | disclosed |
| EP-2295503-A1 | Dibenzorhodamine dyes useful as fluorescent labelling agents | Applera Corporation (US) | 2011-03-16 | — | — | EP | disclosed |
| EP-2295503-A1 | Dibenzorhodamine dyes useful as fluorescent labelling agents | Applera Corporation (US) | 2011-03-16 | — | — | EP | disclosed |
| US-7833756-B2 | Methods of labelling polynucleotides with dibenzorhodamine dyes | APPLIED BIOSYSTEMS, LLC (US) | 2010-11-16 | — | — | US | disclosed |
| EP-2221347-A1 | Sulfonated diarylrhodamine dyes | Applera Corporation (US) | 2010-08-25 | — | — | EP | disclosed |
| EP-2186801-A2 | Intermediates for synthesizing dibenzorhodamine dyes | Applera Corporation (US) | 2010-05-19 | — | — | EP | disclosed |
| EP-2186801-A2 | Intermediates for synthesizing dibenzorhodamine dyes | Applera Corporation (US) | 2010-05-19 | — | — | EP | disclosed |
| EP-2179996-A1 | Sulfonated diarylrhodamine dyes | Applera Corporation (US) | 2010-04-28 | — | — | EP | disclosed |
| WO-2002044416-A2 | SULFONATED DIARYLRHODAMINE DYES AS FLUORESCENT LABELS | APPLERA CORPORATION (US) | 2002-06-06 | — | — | WO | disclosed |
| US-20020034761-A1 | Methods of labelling polynucleotides with dibenzorhodamine dyes | THE PERKIN-ELMER CORPORATION (US) | 2002-03-21 | — | — | US | disclosed |
| US-6326153-B2 | POLYNUCLEOTIDE SEQUENCING | THE PERKIN-ELMER CORPORATION | 2001-12-04 | — | — | US | disclosed |
| US-20010011139-A1 | Polynucleotides labeled with dibenzorhodamine dyes | THE PERKIN-ELMER CORPORATION | 2001-08-02 | — | — | US | disclosed |
| US-6221606-B1 | ENERGY TRANSFER DYE COMPRISING A DONOR DYE WHICH ABSORBS IGHT AND EMITS EXITATION ENERGY, AN ACCEPTOR DYE THE ABSORBS THE EXCITATION ENERGY AND FLUORESCES IN RESPONSE, AND A LINKER LINKING THE TWO DYES, AT LEAST ONE IS A DIBENZORHODAMINE DYE | THE PERKIN-ELMER CORPORATION | 2001-04-24 | — | — | US | disclosed |
| EP-1034221-A1 | DIBENZORHODAMINE DYES USEFUL AS FLUORESCENT LABELLING AGENTS | THE PERKIN-ELMER CORPORATION (US) | 2000-09-13 | — | — | EP | disclosed |
| US-6111116-A | FLUORESCENT LABELING REAGENTS | THE PERKIN-ELMER CORPORATION (US) | 2000-08-29 | — | — | US | disclosed |
| US-6051719-A | FLUORESCENT LABELING REAGENTS | THE PERKIN-ELMER CORPORATION (US) | 2000-04-18 | — | — | US | disclosed |
| US-5936087-A | FLUORESCENT LABELS; DNA SEQUENCING | THE PERKIN-ELMER CORPORATION (US) | 1999-08-10 | — | — | US | disclosed |
| WO-1999027020-A1 | DIBENZORHODAMINE DYES USEFUL AS FLOURESCENT LABELLING AGENTS | THE PERKIN-ELMER CORPORATION (US) | 1999-06-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020034761-A1 | Methods of labelling polynucleotides with dibenzorhodamine dyes | NUDT1, DUT, NSUN2 | MAPT 4668/4885ALDH1A1 1831/4885NPSR1 1456/4885 |
| US-20010011139-A1 | Polynucleotides labeled with dibenzorhodamine dyes | NUDT1, DNTT, DUT | MAPT 4051/4885ALDH1A1 1223/4885NPSR1 1300/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.