Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 3/20 | 0.38 |
| ▸ | CES1 | P23141 | 3/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16091697 | 0.84 | MAOB (0.50) | LTB4RPOLBMAOASIGMAR1MAOB | |
| SCHEMBL8482393 | 0.83 | SIGMAR1 (0.33) | LTB4RPOLBSIGMAR1 | |
| SCHEMBL8136342 | 0.83 | GAA (0.39) | SIGMAR1CES1 | |
| SCHEMBL8480265 | 0.81 | SIGMAR1 (0.32) | SIGMAR1 | |
| SCHEMBL15686638 | 0.81 | KCNH3 (0.33) | LTB4RSIGMAR1 | |
| SCHEMBL2631387 | 0.81 | KCNH3 (0.33) | LTB4RSIGMAR1 | |
| SCHEMBL13930235 | 0.81 | KIF11 (0.39) | MAOASIGMAR1MAPTHTR2A | |
| SCHEMBL15686651 | 0.81 | KCNH3 (0.33) | LTB4RSIGMAR1 | |
| SCHEMBL18215221 | 0.81 | GAA (0.38) | SIGMAR1CES1 | |
| SCHEMBL13871008 | 0.81 | GAA (0.38) | SIGMAR1CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7718603-B1 | conjugate of active peptidyl fragment having a high affinity with mitochondria and a scavenger for reaction oxygen species, or an enzyme inhibitor of nitric oxide synthase; for drug delivering drugs, or biodrugs of various types; drug targets for treating hemorrhagic shock, cell death apoptosis | UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2010-05-18 | — | — | US | disclosed |
| US-20070161573-A1 | SELECTIVE TARGETING AGENTS FOR MITOCHONDRIA | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070161573-A1 | SELECTIVE TARGETING AGENTS FOR MITOCHONDRIA | HSPE1, HSPA9, AIFM1 | LTB4R 2236/4885L3MBTL1 979/4885POLB 609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.