Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 3/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.31 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
| ▸ | MPO | P05164 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.30 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | PDE5A | O76074 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8470193 | 1.00 | KCNH3 (0.33) | KCNH3CNR2CNR1SIGMAR1TBXAS1 | |
| SCHEMBL8456254 | 1.00 | KCNH3 (0.33) | KCNH3CNR2CNR1SIGMAR1TBXAS1 | |
| SCHEMBL15686642 | 1.00 | KCNH3 (0.33) | KCNH3CNR2CNR1SIGMAR1TBXAS1 | |
| SCHEMBL15686638 | 1.00 | KCNH3 (0.33) | KCNH3CNR2CNR1SIGMAR1TBXAS1 | |
| SCHEMBL15686603 | 1.00 | KCNH3 (0.33) | KCNH3CNR2CNR1SIGMAR1TBXAS1 | |
| SCHEMBL15686651 | 1.00 | KCNH3 (0.33) | KCNH3CNR2CNR1SIGMAR1TBXAS1 | |
| SCHEMBL8482393 | 0.98 | SIGMAR1 (0.33) | KCNH3CNR2CNR1SIGMAR1ESR2 | |
| SCHEMBL8454747 | 0.96 | ESR2 (0.32) | KCNH3SIGMAR1ESR2NR1H2NR1H3 | |
| SCHEMBL13192982 | 0.91 | KDM4E (0.37) | — | |
| SCHEMBL13192948 | 0.91 | ACLY (0.38) | CNR2CNR1TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170145499-A1 | METHODS FOR INDEXING SAMPLES AND SEQUENCING MULTIPLE POLYNUCLEOTIDE TEMPLATES | ILLUMINA CAMBRIDGE LIMITED (US) | 2017-05-25 | — | — | US | disclosed |
| US-20170021325-A1 | Preparation of Templates for Nucleic Acid Sequencing | SOLEXA LIMITED (GB) | 2017-01-26 | — | — | US | disclosed |
| US-9512478-B2 | Methods for indexing samples and sequencing multiple polynucleotide templates | ILLUMINA CAMBRIDGE LIMITED (GB) | 2016-12-06 | — | — | US | disclosed |
| US-9498763-B2 | Preparation of templates for nucleic acid sequencing | ILLUMINA CAMBRIDGE LIMITED (GB) | 2016-11-22 | — | — | US | disclosed |
| US-9422318-B2 | Epoxyeicosatrienoic acid analogs and methods of making and using the same | THE MEDICAL COLLEGE OF WISCONSIN, INC. (US) | 2016-08-23 | — | — | US | disclosed |
| US-20160090623-A1 | METHOD FOR PAIRWISE SEQUENCING OF TARGET POLYNUCLEOTIDES | ILLUMINA CAMBRIDGE LIMITED (GB) | 2016-03-31 | — | — | US | disclosed |
| US-9267173-B2 | Method for pairwise sequencing of target polynucleotides | ILLUMINA CAMBRIDGE LIMITED (GB) | 2016-02-23 | — | — | US | disclosed |
| US-20150343410-A1 | Preparation of Templates for Nucleic Acid Sequencing | ILLUMINA CAMBRIDGE LIMITED (GB) | 2015-12-03 | — | — | US | disclosed |
| US-20150336916-A1 | EPOXYEICOSATRIENOIC ACID ANALOGS AND METHODS OF MAKING AND USING THE SAME | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-11-26 | — | — | US | disclosed |
| US-9127027-B2 | Epoxyeicosatrienoic acid analogs and methods of making and using the same | THE MEDICAL COLLEGE OF WISCONSIN, INC. (US) | 2015-09-08 | — | — | US | disclosed |
| US-8236505-B2 | Method for pairwise sequencing of target polynucleotides | ILLUMINA CAMBRIDGE LIMITED (GB) | 2012-08-07 | — | — | US | disclosed |
| US-8182989-B2 | Methods for indexing samples and sequencing multiple polynucleotide templates | ILLUMINA CAMBRIDGE LTD. (GB) | 2012-05-22 | — | — | US | disclosed |
| US-20120094848-A1 | Method for pairwise sequencing of target polynucleotides | ILLUMINA CAMBRIDGE LIMITED (GB) | 2012-04-19 | — | — | US | disclosed |
| US-20120015823-A1 | Methods for indexing samples and sequencing multiple polynucleotide templates | ILLUMINA CAMBRIDGE LIMITED (GB) | 2012-01-19 | — | — | US | disclosed |
| US-7960120-B2 | Method for pair-wise sequencing a plurality of double stranded target polynucleotides | ILLUMINA CAMBRIDGE LTD. (GB) | 2011-06-14 | — | — | US | disclosed |
| EP-2298930-A1 | Preparation of templates for nucleic acid sequencing | Illumina Cambridge Limited (GB) | 2011-03-23 | — | — | EP | disclosed |
| US-20110014657-A1 | Method for sequencing a polynucleotide template | ILLUMINA CAMBRIDGE LTD. | 2011-01-20 | — | — | US | disclosed |
| US-7754429-B2 | Method for pair-wise sequencing a plurity of target polynucleotides | ILLUMINA CAMBRIDGE LIMITED (GB) | 2010-07-13 | — | — | US | disclosed |
| US-20090118128-A1 | Preparation of templates for nucleic acid sequencing | ILLUMINA CAMBRIDGE LIMITED (GB) | 2009-05-07 | — | — | US | disclosed |
| US-20090088327-A1 | Method for sequencing a polynucleotide template | SOLEXA LIMITED (GB) | 2009-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150336916-A1 | EPOXYEICOSATRIENOIC ACID ANALOGS AND METHODS OF MAKING AND USING THE SAME | PTGER1, PTGES, PTGER2 | KCNH3 4426/4885CNR2 390/4885CNR1 546/4885 |
| US-20090118128-A1 | Preparation of templates for nucleic acid sequencing | RNGTT, POLRMT, POLM | KCNH3 4305/4885CNR2 4573/4885CNR1 4500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.