Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 3/20 | 0.60 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.60 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6786842 | 0.86 | ADRB2 (0.59) | ADRB3ADRB2ADRB1KDM1AMAOA | |
| SCHEMBL25251683 | 0.83 | ADRB1 (0.66) | ADRB3ADRB2ADRB1KDM1AMAOA | |
| SCHEMBL16314531 | 0.83 | CA12 (0.64) | ADRB3ADRB2ADRB1KDM4EPTGS1 | |
| SCHEMBL9644865 | 0.81 | ALDH1A1 (0.56) | ADRB3ADRB2ADRB1KDM4EKDM1A | |
| SCHEMBL6049252 | 0.81 | TDP1 (0.55) | ADRB3ADRB2ADRB1KDM4EPTGS1 | |
| SCHEMBL5390387 | 0.81 | PTGS1 (0.74) | ADRB3ADRB2ADRB1KDM4EPTGS1 | |
| SCHEMBL7934862 | 0.80 | MAPT (0.55) | ADRB3ADRB2ADRB1KDM4EMAOA | |
| Alcohol SCHEMBL11163523 | 0.80 | PTGS1 (0.68) | ADRB3ADRB2ADRB1KDM4EPTGS1 | |
| SCHEMBL13895634 | 0.80 | LMNA (0.72) | ADRB3ADRB2ADRB1KDM4ECA12 | |
| SCHEMBL6643064 | 0.79 | CYP2D6 (0.72) | ADRB3ADRB2ADRB1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1844048-B1 | PYRAZOLOPYRIMIDINES AS CELL CYCLE KINASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2010-05-26 | — | — | EP | disclosed |