SCHEMBL13367459

SCHEMBL13367459

CN(c1ccc(-c2ccccc2)cc1)c1cc2ccccc2c2ccccc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.40
PDE5A O76074 2/20 0.40
CHKA P35790 5/20 0.39
MAPT P10636 3/20 0.38
HPGD P15428 3/20 0.38
LMNA P02545 2/20 0.38
TSHR P16473 2/20 0.38
ALOX15 P16050 1/20 0.38
ALDH1A1 P00352 3/20 0.36
HIF1A Q16665 2/20 0.36
KDM4E B2RXH2 2/20 0.36
CHKB Q9Y259 1/20 0.36
CYP1A2 P05177 1/20 0.36
GLA P06280 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
RECQL P46063 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12048622 0.95 GPR84 (0.39) GPR84L3MBTL1PDE5ACHKAMAPT
SCHEMBL12048129 0.95 GPR84 (0.39) GPR84L3MBTL1PDE5ACHKAMAPT
SCHEMBL12048344 0.94 PDE5A (0.39) GPR84L3MBTL1PDE5ACHKAMAPT
SCHEMBL12047845 0.94 PDE5A (0.39) GPR84L3MBTL1PDE5ACHKAMAPT
SCHEMBL12048273 0.92 CHKA (0.39) GPR84L3MBTL1PDE5ACHKAMAPT
SCHEMBL12048720 0.90 TRPM4 (0.41) PDE5ACHKAMAPTHPGDLMNA
SCHEMBL21422645 0.89 HPRT1 (0.42) L3MBTL1PDE5ACHKAMAPTHPGD
SCHEMBL24327693 0.89 ESR1 (0.42) GPR84L3MBTL1CHKAMAPTHPGD
SCHEMBL24327740 0.89 ESR1 (0.42) GPR84L3MBTL1CHKAMAPTHPGD
SCHEMBL12048002 0.89 SIGMAR1 (0.38) GPR84L3MBTL1PDE5ACHKAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10730812-B2 Double spiro compound and organic light-emitting element comprising same LG CHEM, LTD. (KR) 2020-08-04 US disclosed
US-10651411-B2 Compound and organic light emitting device containing same LG CHEM, LTD. (KR) 2020-05-12 US disclosed
WO-2019189037-A1 FUSED-RING COMPOUND, METHOD FOR PRODUCING SAME, AND PRODUCTION INTERMEDIATE THEREOF 東ソー株式会社 2019-10-03 WO disclosed
US-10421721-B2 Heterocyclic compound and organic light emitting device comprising same LG CHEM, LTD. (KR) 2019-09-24 US disclosed
US-20180148641-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2018-05-31 US disclosed
US-20180145272-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE CONTAINING SAME LG CHEM, LTD. (KR) 2018-05-24 US disclosed
US-20180145272-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE CONTAINING SAME LG CHEM, LTD. (KR) 2018-05-24 US disclosed
US-9960357-B2 Spiro-type compound and organic light emitting element comprising same LG CHEM, LTD. (KR) 2018-05-01 US disclosed
US-9960357-B2 Spiro-type compound and organic light emitting element comprising same LG CHEM, LTD. (KR) 2018-05-01 US disclosed
US-20180111887-A1 DOUBLE SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2018-04-26 US disclosed
US-20180111887-A1 DOUBLE SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2018-04-26 US disclosed
US-20180037547-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME LG CHEM, LTD. (KR) 2018-02-08 US disclosed
US-20180037547-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME LG CHEM, LTD. (KR) 2018-02-08 US disclosed
US-20170365787-A1 SPIRO-TYPE COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2017-12-21 US disclosed
US-20170365787-A1 SPIRO-TYPE COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2017-12-21 US disclosed
US-20100108997-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-05-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180145272-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE CONTAINING SAME CRY1, CRY2, OR10J3 GPR84 835/4885L3MBTL1 349/4885PDE5A 3284/4885
US-10651411-B2 Compound and organic light emitting device containing same CRY1, CRY2, OR10J3 GPR84 835/4885L3MBTL1 349/4885PDE5A 3284/4885
US-10421721-B2 Heterocyclic compound and organic light emitting device comprising same CRY1, CRY2, PER2 GPR84 1477/4885L3MBTL1 856/4885PDE5A 3873/4885
US-20180037547-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME CRY1, CRY2, PER2 GPR84 1477/4885L3MBTL1 856/4885PDE5A 3873/4885
US-20100108997-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same OR10J3, OCIAD1, OCIAD2 GPR84 994/4885L3MBTL1 538/4885PDE5A 4323/4885
US-20180148641-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME CRY1, CRY2, PER2 GPR84 2132/4885L3MBTL1 962/4885PDE5A 4509/4885
US-10730812-B2 Double spiro compound and organic light-emitting element comprising same NR2E3, CRY1, CRY2 GPR84 1896/4885L3MBTL1 2738/4885PDE5A 4054/4885
US-20180111887-A1 DOUBLE SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME NR2E3, CRY1, CRY2 GPR84 1896/4885L3MBTL1 2738/4885PDE5A 4054/4885
US-20170365787-A1 SPIRO-TYPE COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME CRY1, NR2E3, LEF1 GPR84 1759/4885L3MBTL1 3362/4885PDE5A 3966/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.