SCHEMBL13380264

SCHEMBL13380264

CC1CC(C)C(OC(=O)c2c(-c3ccccc3)c[nH]c2NC(=O)c2cccc(C(F)(F)F)c2)C(C)C1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.48
LMNA P02545 1/20 0.43
KCNK3 O14649 1/20 0.41
RXFP1 Q9HBX9 2/20 0.41
GAA P10253 1/20 0.40
ADCY1 Q08828 1/20 0.40
TAS1R3 Q7RTX0 1/20 0.40
TAS1R1 Q7RTX1 1/20 0.40
TAS1R2 Q8TE23 1/20 0.40
PTPN1 P18031 1/20 0.39
ESR1 P03372 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
P2RX1 P51575 1/20 0.39
RAF1 P04049 1/20 0.38
PTGS1 P23219 1/20 0.38
MEN1 O00255 1/20 0.38
HTT P42858 1/20 0.38
RAB9A P51151 1/20 0.38
KMT2A Q03164 1/20 0.38
MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13380260 0.88 GAA (0.45) LMNAKCNK3GAATAS1R3TAS1R1
SCHEMBL13380249 0.82 ALDH1A1 (0.41) ALDH1A1LMNAKCNK3RXFP1GAA
SCHEMBL13380256 0.78 MEN1 (0.40) LMNAKCNK3GAATAS1R3TAS1R1
SCHEMBL13380259 0.71 TAS1R3 (0.36) LMNAKCNK3RXFP1GAATAS1R3
SCHEMBL28637086 0.67 CES2 (0.54) ALDH1A1LMNAGAATAS1R3TAS1R1
SCHEMBL15448814 0.64 HTT (0.41) ALDH1A1LMNANPSR1MEN1HTT
SCHEMBL25796418 0.63 CES2 (0.49) ALDH1A1LMNAKCNK3NPSR1P2RX1
SCHEMBL27052122 0.63 CES2 (0.49) ALDH1A1LMNAKCNK3NPSR1P2RX1
SCHEMBL30739929 0.63 LMNA (1.00) ALDH1A1LMNAKCNK3RXFP1GAA
SCHEMBL4517587 0.63 LMNA (1.00) ALDH1A1LMNAKCNK3RXFP1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8343696-B2 Colored curable composition, fluorine-containing dipyrromethene compound and tautomer thereof, and fluorine-containing dipyrromethene metal complex and tautomer thereof, and color filter using the same and method for producing the color filter FUJIFILM CORPORATION (JP) 2013-01-01 US disclosed
US-20100081071-A1 COLORED CURABLE COMPOSITION, FLUORINE-CONTAINING DIPYRROMETHENE COMPOUND AND TAUTOMER THEREOF, AND FLUORINE-CONTAINING DIPYRROMETHENE METAL COMPLEX AND TAUTOMER THEREOF, AND COLOR FILTER USING THE SAME AND METHOD FOR PRODUCING THE COLOR FILTER FUJIFILM CORPORATION (JP) 2010-04-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100081071-A1 COLORED CURABLE COMPOSITION, FLUORINE-CONTAINING DIPYRROMETHENE COMPOUND AND TAUTOMER THEREOF, AND FLUORINE-CONTAINING DIPYRROMETHENE METAL COMPLEX AND TAUTOMER THEREOF, AND COLOR FILTER USING THE SAME AND METHOD FOR PRODUCING THE COLOR FILTER SCO2, TDO2, FTH1 ALDH1A1 1144/4885LMNA 3670/4885KCNK3 3247/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.