Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Hexamethonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 known ✓ | O00255 | 4/20 | 0.85 |
| ▸ | ACHE known ✓ | P22303 | 3/20 | 0.85 |
| ▸ | APEX1 | P27695 | 3/20 | 0.92 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.92 |
| ▸ | LMNA | P02545 | 2/20 | 0.86 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.85 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.85 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.85 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.85 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.85 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.85 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.85 |
| ▸ | TSHR | P16473 | 1/20 | 0.85 |
| ▸ | RAB9A | P51151 | 1/20 | 0.85 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.71 |
| ▸ | APAF1 | O14727 | 1/20 | 0.67 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.67 |
| ▸ | RAD52 | P43351 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3679398 | 0.96 | APEX1 (1.00) | APEX1NPSR1LMNAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6012972 | 0.96 | APEX1 (1.00) | APEX1NPSR1LMNAMEN1KMT2A | |
| Pentamethonium SCHEMBL8914783 | 0.96 | APEX1 (1.00) | APEX1NPSR1LMNAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6012951 | 0.96 | APEX1 (1.00) | APEX1NPSR1LMNAMEN1KMT2A | |
| Decamethonium SCHEMBL2831663 | 0.96 | APEX1 (1.00) | APEX1NPSR1LMNAMEN1KMT2A | |
| Decamethonium SCHEMBL323468 | 0.96 | APEX1 (1.00) | APEX1NPSR1LMNAMEN1KMT2A | |
| Decamethonium SCHEMBL2830377 | 0.96 | APEX1 (1.00) | APEX1NPSR1LMNAMEN1KMT2A | |
| Hexamethonium SCHEMBL22332 | 0.96 | APEX1 (1.00) | APEX1NPSR1LMNAMEN1KMT2A | |
| Hexamethonium SCHEMBL9903433 | 0.92 | LMNA (0.86) | APEX1NPSR1LMNAMEN1KMT2A | |
| Hexamethonium SCHEMBL4381389 | 0.92 | LMNA (1.00) | APEX1NPSR1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090092913-A1 | ADDITIVE CONTAINING PHOTOGENERATING LAYER PHOTOCONDUCTORS | XEROX CORPORATION (US) | 2009-04-09 | — | — | US | claimed |
| US-20090092911-A1 | ADDITIVE CONTAINING CHARGE TRANSPORT LAYER PHOTOCONDUCTORS | XEROX CORPORATION (US) | 2009-04-09 | — | — | US | claimed |
| US-20250270153-A1 | ZEOLITE WITH IMPROVED HYDRO-ISOMERIZATION ACTIVITY | SK INNOVATION CO LTD (KR) | 2025-08-28 | — | — | US | disclosed |
| US-12338212-B2 | Zeolite with improved hydro-isomerization activity | SK INNOVATION CO., LTD. (KR) | 2025-06-24 | — | — | US | disclosed |
| US-12264275-B2 | Treatment liquid | FUJIFILM CORPORATION (JP) | 2025-04-01 | — | — | US | disclosed |
| US-12247298-B2 | Semiconductor wafer treatment liquid and production method thereof | TOKUYAMA CORPORATION (JP) | 2025-03-11 | — | — | US | disclosed |
| CN-117583020-A | Zeolite having improved hydroisomerization reactivity | SK新技术株式会社 | 2024-02-23 | — | — | CN | disclosed |
| US-20240059631-A1 | ZEOLITE WITH IMPROVED HYDRO-ISOMERIZATION ACTIVITY | SK ENMOVE CO., LTD. (KR) | 2024-02-22 | — | — | US | disclosed |
| EP-4324556-A1 | ZEOLITE WITH IMPROVED HYDROISOMERIZATION ACTIVITY | SK Innovation Co., Ltd. (KR) | 2024-02-21 | — | — | EP | disclosed |
| EP-4269656-A1 | SEMICONDUCTOR WAFER TREATMENT SOLUTION AND PRODCTION METHOD FOR SAME | Tokuyama Corporation (JP) | 2023-11-01 | — | — | EP | disclosed |
| US-11724249-B2 | Cu—P co-supported zeolite, and selective catalytic reduction catalyst and catalyst for exhaust gas using same | N.E. CHEMCAT CORPORATION (JP) | 2023-08-15 | — | — | US | disclosed |
| US-7709168-B2 | Phosphonium containing charge transport layer photoconductors | XEROX CORPORATION (US) | 2010-05-04 | — | — | US | disclosed |
| US-7687212-B2 | Charge trapping releaser containing photogenerating layer photoconductors | XEROX CORPORATION (US) | 2010-03-30 | — | — | US | disclosed |
| US-20090092912-A1 | IMIDAZOLIUM SALT CONTAINING CHARGE TRANSPORT LAYER PHOTOCONDUCTORS | XEROX CORPORATION (US) | 2009-04-09 | — | — | US | disclosed |
| US-20090092913-A1 | ADDITIVE CONTAINING PHOTOGENERATING LAYER PHOTOCONDUCTORS | XEROX CORPORATION (US) | 2009-04-09 | — | — | US | disclosed |
| US-20090092915-A1 | PHOSPHONIUM CONTAINING CHARGE TRANSPORT LAYER PHOTOCONDUCTORS | XEROX CORPORATION (US) | 2009-04-09 | — | — | US | disclosed |
| US-20090092914-A1 | PHOSPHONIUM CONTAINING PHOTOGENERATING LAYER PHOTOCONDUCTORS | XEROX CORPORATION (US) | 2009-04-09 | — | — | US | disclosed |
| US-20090092909-A1 | CHARGE TRAPPING RELEASER CONTAINING PHOTOGENERATING LAYER PHOTOCONDUCTORS | XEROX CORPORATION (US) | 2009-04-09 | — | — | US | disclosed |
| US-20090092908-A1 | CHARGE TRAPPING RELEASER CONTAINING CHARGE TRANSPORT LAYER PHOTOCONDUCTORS | XEROX CORPORATION (US) | 2009-04-09 | — | — | US | disclosed |
| US-20090092911-A1 | ADDITIVE CONTAINING CHARGE TRANSPORT LAYER PHOTOCONDUCTORS | XEROX CORPORATION (US) | 2009-04-09 | — | — | US | disclosed |