SCHEMBL78935

SCHEMBL78935

Nc1cccc(C2CCc3ccccc32)c1N

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 4/20 0.44
ADRA1A P35348 1/20 0.44
CYP11B2 P19099 4/20 0.42
CYP19A1 P11511 3/20 0.42
HTR6 P50406 3/20 0.41
PDPK1 O15530 1/20 0.41
SIGMAR1 Q99720 1/20 0.40
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
RET P07949 1/20 0.39
HTR2A P28223 1/20 0.39
CYP17A1 P05093 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2984209 0.87 IDO1 (0.48) IDO1ADRA1ACYP11B2CYP19A1HTR6
SCHEMBL10492671 0.83 IDO1 (0.40) IDO1ADRA1ACYP11B2CYP19A1HTR6
SCHEMBL10500854 0.79 HTR6 (0.50) IDO1ADRA1ACYP11B2CYP19A1HTR6
SCHEMBL11696770 0.76 IDO1 (0.51) IDO1ADRA1AHTR6RETHTR2A
SCHEMBL133896 0.76 HTR2A (0.49) IDO1ADRA1ACYP11B2PDPK1SIGMAR1
SCHEMBL10492557 0.74 GID4 (0.47) IDO1ADRA1AHTR6
SCHEMBL2242767 0.74 KDM4E (0.44) IDO1ADRA1ACYP11B2CYP19A1HTR6
SCHEMBL10492532 0.73 HTR6 (0.41) IDO1ADRA1ACYP11B2HTR6PDPK1
SCHEMBL2083374 0.73 PLA2G6 (0.49) IDO1ADRA1ACYP11B2PDPK1SIGMAR1
SCHEMBL9614919 0.73 HTR6 (0.54) IDO1ADRA1ACYP11B2CYP19A1HTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11684894-B2 In situ fabrication of metal-organic framework films and mixed-matrix membranes TEXAS A&M UNIVERSITY (US) 2023-06-27 US claimed
WO-2013141481-A1 FLEXIBLE THIN FILM BATTERY CAPABLE OF WITHSTANDING HIGH TEMPERATURE TREATMENT AND METHOD FOR FABRICATING SAME 지에스칼텍스(주) (KR) 2013-09-26 WO claimed
CN-101528591-B Process for the extraction of hydrogen from a gas mixture Shell int research co ltd 2012-03-14 CN claimed
EP-2074057-B1 PROCESS FOR THE EXTRACTION OF HYDROGEN FROM A GAS MIXTURE SHELL INT RESEARCH (NL) 2011-03-23 EP claimed
US-6569984-B2 Reacting a diamine with an ester acid of a dianhydride to form polyimide VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. 2003-05-27 US claimed
US-20020022710-A1 Method for making polyimide VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. 2002-02-21 US claimed
WO-2001081453-A1 METHOD FOR MAKING POLYIMIDE VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) 2001-11-01 WO claimed
US-5543493-A IMMERSION IN AMINE SOLUTIONS IMPROVES ADHESION SAMSUNG ELECTRONICS CO., LTD. (KR) 1996-08-06 US claimed
US-5153303-A Polyimides prepared from disubstituted aromatic tetracarboxylic acid dianhydrides CIBA-GEIGY CORPORATION (US) 1992-10-06 US claimed
EP-0438382-A1 Disubstituted aromatic dianhydrides and polyimides prepared therefrom CIBA-GEIGY AG (CH) 1991-07-24 EP claimed
EP-0227598-B1 STABLE COMPOSITIONS CONTAINING IMIDES CIBA-GEIGY AG (CH) 1989-08-02 EP claimed
US-4749767-A IMPREGNATED YARN LAMINATE CIBA-GEIGY CORPORATION (US) 1988-06-07 US claimed
EP-0227598-A1 Stable compositions containing imides CIBA-GEIGY AG (CH) 1987-07-01 EP claimed
EP-0099338-B1 EPOXY RESIN SYSTEMS MODIFIED WITH THERMOPLASTIC RESINS CIBA-GEIGY AG (CH) 1986-05-14 EP claimed
EP-0099338-A1 Epoxy resin systems modified with thermoplastic resins CIBA-GEIGY AG (CH) 1984-01-25 EP claimed
EP-4721842-A1 MEMBRANE-BASED PROCESS GAS DRYING WITH LOW PRESSURE GASEOUS STREAMS SYSTEM AND METHOD Haffmans B.V. (NL) 2026-04-08 EP disclosed
US-20260091347-A1 MEMBRANE-BASED PROCESS GAS DRYING WITH LOW PRESSURE GASEOUS STREAMS SYSTEM AND METHOD HAFFMANS BV (NL) 2026-04-02 US disclosed
EP-0099338-A1 Epoxy resin systems modified with thermoplastic resins CIBA-GEIGY AG (CH) 1984-01-25 EP disclosed
US-4388132-A Method of attaching a protective film to an integrated circuit BURROUGHS CORPORATION (US) 1983-06-14 US disclosed
US-4026876-A Soluble polyamide-imides derived from phenylindane diamines CIBA-GEIGY CORPORATION (US) 1977-05-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260091347-A1 MEMBRANE-BASED PROCESS GAS DRYING WITH LOW PRESSURE GASEOUS STREAMS SYSTEM AND METHOD AQP4, AQP1, AQP3 IDO1 4543/4885ADRA1A 3366/4885CYP11B2 1787/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.