Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 7/20 | 0.33 |
| ▸ | ANPEP | P15144 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8867224 | 0.90 | MMP2 (0.39) | TSHRMMP2ANPEP | |
| SCHEMBL8866598 | 0.90 | MMP2 (0.39) | TSHRMMP2ANPEP | |
| SCHEMBL3301765 | 0.89 | TSHR (0.36) | TSHRMMP2ANPEPTHRB | |
| SCHEMBL3307394 | 0.89 | TSHR (0.36) | TSHRMMP2ANPEPTHRB | |
| SCHEMBL6798706 | 0.89 | TSHR (0.36) | TSHRMMP2ANPEPTHRB | |
| SCHEMBL8983770 | 0.89 | TSHR (0.36) | TSHRMMP2ANPEPTHRB | |
| SCHEMBL25475425 | 0.84 | ALDH1A1 (0.32) | TSHRMMP2ANPEPTHRB | |
| SCHEMBL7058824 | 0.84 | ALDH1A1 (0.32) | TSHRMMP2ANPEPTHRB | |
| SCHEMBL3302863 | 0.84 | ALDH1A1 (0.32) | TSHRMMP2ANPEPTHRB | |
| SCHEMBL13390275 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100094014-A1 | EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | MARTINEZ-PEREZ JOSE ANTONIO | 2010-04-15 | — | — | US | disclosed |
| US-7601738-B2 | Excitatory amino acid receptor antagonists | ELI LILLY AND COMPANY (US) | 2009-10-13 | — | — | US | disclosed |
| US-7205313-B2 | Excitatory amino acid receptor antagonists | ELI LILLY AND COMPANY (US) | 2007-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100094014-A1 | EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | SLC1A2, SLC1A1, GRIN1 | TSHR 642/4885MMP2 4471/4885ANPEP 668/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.