Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | RXRG | P48443 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RBP4 | P02753 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 4/20 | 0.37 |
| ▸ | CTRC | Q99895 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8935730 | 0.79 | PPARG (0.54) | PPARGRXRARXRBRXRGATM | |
| SCHEMBL8935731 | 0.79 | PPARG (0.54) | PPARGRXRARXRBRXRGATM | |
| SCHEMBL9623616 | 0.78 | RXRA (0.51) | PPARGRXRARXRBRXRGTDP1 | |
| SCHEMBL30639267 | 0.75 | CTRC (0.54) | PPARGKDM4EALDH1A1PPARACTRC | |
| SCHEMBL9698444 | 0.74 | PPARG (0.46) | PPARGKDM4EALDH1A1PPARACTRC | |
| SCHEMBL13673933 | 0.71 | ALDH1A1 (0.60) | RXRARXRBRXRGATMTDP1 | |
| SCHEMBL5696283 | 0.71 | KMT2A (0.62) | PPARGRXRARXRBRXRGATM | |
| SCHEMBL11521450 | 0.70 | KMT2A (0.53) | PPARGALDH1A1PPARACTRCPTGES | |
| SCHEMBL14565994 | 0.70 | CTRC (0.50) | PPARGTDP1KDM4EALDH1A1PPARA | |
| SCHEMBL568454 | 0.70 | CTRC (0.50) | PPARGATMKDM4EALDH1A1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8530634-B2 | Method of oligonucleotide labeling using cycloaddition reaction | CHEMGENES CORPORATION (US) | 2013-09-10 | — | — | US | disclosed |
| US-20120058476-A1 | Method Of Oligonucleotide Labeling Using Cycloaddition Reaction | CHEMGENES CORPORATION | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120058476-A1 | Method Of Oligonucleotide Labeling Using Cycloaddition Reaction | CBR3, CYB5R3, DUT | PPARG 3937/4885RXRA 2266/4885RXRB 1655/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.