Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.37 |
| ▸ | CA12 | O43570 | 6/20 | 0.35 |
| ▸ | CA1 | P00915 | 6/20 | 0.35 |
| ▸ | CA2 | P00918 | 6/20 | 0.35 |
| ▸ | CA4 | P22748 | 6/20 | 0.35 |
| ▸ | CA9 | Q16790 | 6/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13396388 | 0.92 | CA12 (0.39) | PTGS2CA12CA1CA2CA4 | |
| SCHEMBL13396493 | 0.87 | KCNH2 (0.36) | PTGS2CA12CA1CA2CA4 | |
| SCHEMBL13396357 | 0.85 | ALOX5 (0.44) | PTGS2PTGS1 | |
| SCHEMBL13396468 | 0.85 | FFAR1 (0.39) | PTGS2PTGS1KCNH2 | |
| SCHEMBL13396366 | 0.85 | SLC7A5 (0.43) | PTGS2 | |
| SCHEMBL13396440 | 0.84 | ITGB3 (0.40) | CA12CA1CA2CA4CA9 | |
| SCHEMBL13396540 | 0.82 | HTR2A (0.39) | PTGS2CA12CA1CA2CA4 | |
| SCHEMBL13396479 | 0.80 | FFAR1 (0.39) | PTGS2CA12CA1CA2CA4 | |
| SCHEMBL13396412 | 0.79 | NPY4R (0.37) | CA12CA1CA2CA9 | |
| SCHEMBL13416252 | 0.78 | PTGS2 (0.39) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9266820-B2 | Nitric oxide donor compounds | NICOX SCIENCE IRELAND (IE) | 2016-02-23 | — | — | US | disclosed |
| US-20140288142-A1 | NITRIC OXIDE DONOR COMPOUNDS | NICOX SA (FR) | 2014-09-25 | — | — | US | disclosed |
| US-20100099729-A1 | NITRIC OXIDE DONOR COMPOUNDS | NICOX S.A. (FR) | 2010-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140288142-A1 | NITRIC OXIDE DONOR COMPOUNDS | NOS3, NOS2, NOS1 | PTGS2 15/4885CA12 4275/4885CA1 4365/4885 |
| US-20100099729-A1 | NITRIC OXIDE DONOR COMPOUNDS | NOS3, NOS2, NOS1 | PTGS2 12/4885CA12 4290/4885CA1 4414/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.