Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.38 |
| ▸ | FDFT1 | P37268 | 4/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13396434 | 0.95 | MTNR1A (0.36) | MTNR1AMTNR1BFDFT1FAAHALOX5 | |
| SCHEMBL13105641 | 0.90 | TMEM97 (0.38) | — | |
| SCHEMBL13396398 | 0.89 | NPY4R (0.37) | — | |
| SCHEMBL13416894 | 0.85 | MTNR1A (0.39) | MTNR1AMTNR1BFDFT1FAAH | |
| SCHEMBL13396512 | 0.84 | ACHE (0.40) | ALOX5 | |
| SCHEMBL13396412 | 0.84 | NPY4R (0.37) | — | |
| SCHEMBL13396500 | 0.82 | PTGS1 (0.39) | FDFT1ALOX5 | |
| SCHEMBL13396358 | 0.82 | ALOX5 (0.42) | MTNR1AMTNR1BFDFT1ALOX5 | |
| SCHEMBL13416874 | 0.82 | MTNR1A (0.37) | MTNR1AMTNR1BFDFT1FAAH | |
| SCHEMBL13396514 | 0.81 | ALOX5 (0.39) | MTNR1AMTNR1BFDFT1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9266820-B2 | Nitric oxide donor compounds | NICOX SCIENCE IRELAND (IE) | 2016-02-23 | — | — | US | disclosed |
| US-20140288142-A1 | NITRIC OXIDE DONOR COMPOUNDS | NICOX SA (FR) | 2014-09-25 | — | — | US | disclosed |
| US-20100099729-A1 | NITRIC OXIDE DONOR COMPOUNDS | NICOX S.A. (FR) | 2010-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140288142-A1 | NITRIC OXIDE DONOR COMPOUNDS | NOS3, NOS2, NOS1 | MTNR1A 143/4885MTNR1B 55/4885FDFT1 1553/4885 |
| US-20100099729-A1 | NITRIC OXIDE DONOR COMPOUNDS | NOS3, NOS2, NOS1 | MTNR1A 161/4885MTNR1B 76/4885FDFT1 1243/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.