Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 10/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2657985 | 0.85 | ALDH1A1 (0.65) | SIGMAR1ALDH1A1KDM4EMAPK1SMN1; SMN2 | |
| SCHEMBL29531890 | 0.85 | ALDH1A1 (0.65) | SIGMAR1ALDH1A1KDM4EMAPK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2926248 | 0.84 | ALDH1A1 (0.64) | SIGMAR1ALDH1A1KDM4EMAPK1SMN1; SMN2 | |
| SCHEMBL21961925 | 0.79 | SIGMAR1 (0.71) | SIGMAR1TDP1MEN1KMT2A | |
| SCHEMBL1259602 | 0.79 | SIGMAR1 (0.71) | SIGMAR1TDP1MEN1KMT2A | |
| Bromide SCHEMBL1259195 | 0.77 | SIGMAR1 (0.69) | SIGMAR1ALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL6383841 | 0.76 | SIGMAR1 (0.62) | SIGMAR1ALDH1A1TDP1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL27637901 | 0.75 | SIGMAR1 (0.61) | SIGMAR1ALDH1A1TDP1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4838680 | 0.75 | SIGMAR1 (0.61) | SIGMAR1TDP1MEN1KMT2ACHRM3 | |
| Hydrochloric Acid SCHEMBL27637891 | 0.75 | SIGMAR1 (0.61) | SIGMAR1TDP1MEN1KMT2ACHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100081661-A1 | HEME OXYGENASE INHIBITORS, SCREENING METHODS FOR HEME OXYGENASE INHIBITORS AND METHODS OF USE OF HEME OXYGENASE INHIBITORS FOR ANTIMICROBIAL THERAPY | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2010-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100081661-A1 | HEME OXYGENASE INHIBITORS, SCREENING METHODS FOR HEME OXYGENASE INHIBITORS AND METHODS OF USE OF HEME OXYGENASE INHIBITORS FOR ANTIMICROBIAL THERAPY | HMOX1, HMOX2, PPOX | SIGMAR1 1677/4885ALDH1A1 802/4885KDM4E 2274/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.