Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 2/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.52 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.52 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.52 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.52 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.52 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21413027 | 0.88 | ALDH1A1 (0.43) | CHRM1CHRM2CHRM4CHRM5CHRNB2 | |
| Hydrochloric Acid SCHEMBL31452991 | 0.82 | CHRM1 (0.47) | CHRM1CHRM2CHRM4CHRM5CHRNB2 | |
| SCHEMBL21413021 | 0.82 | SCN5A (0.36) | CHRM1CHRM2CHRM4CHRM5CHRNB2 | |
| SCHEMBL3036708 | 0.82 | CHRM1 (0.65) | CHRM1CHRM2CHRM4CHRM5CHRNB2 | |
| SCHEMBL13133071 | 0.82 | TSHR (0.46) | CHRNB2CHRNA4CA12CA1CA2 | |
| SCHEMBL19500129 | 0.82 | CHRM1 (0.50) | CHRM1CHRM2CHRM4CHRM5CHRNB2 | |
| SCHEMBL29768565 | 0.81 | DNM1 (0.38) | CHRM1CHRM2CHRM4CHRM5CHRNB2 | |
| SCHEMBL13407448 | 0.80 | CHRM1 (0.58) | CHRM1CHRM2CHRM4CHRM5CHRNB2 | |
| Hydrochloric Acid SCHEMBL8397227 | 0.80 | CHRM1 (0.62) | CHRM1CHRM2CHRM4CHRM5CHRNB2 | |
| SCHEMBL19500083 | 0.79 | CHRNB2 (0.37) | CHRM1CHRM2CHRM4CHRM5CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0830336-B1 | PROCESS FOR THE PREPARATION OF TERTIARY AMINOCARBONATES AND AMINOETHERS | CROMPTON CORP (US) | 2003-05-21 | — | — | EP | claimed |
| EP-0830336-A4 | PROCESS FOR THE PREPARATION OF TERTIARY AMINOCARBONATES AND AMINOETHERS | OSI SPECIALTIES INC (US) | 2000-04-05 | — | — | EP | claimed |
| EP-0830336-A1 | PROCESS FOR THE PREPARATION OF TERTIARY AMINOCARBONATES AND AMINOETHERS | OSi Specialties, Inc. (US) | 1998-03-25 | — | — | EP | claimed |
| WO-1996040613-A1 | PROCESS FOR THE PREPARATION OF TERTIARY AMINOCARBONATES AND AMINOETHERS | OSI SPECIALTIES, INC. (US) | 1996-12-19 | — | — | WO | claimed |
| US-5563288-A | REACTING DIMETHYL CARBONATE WITH ALCOHOL TO FORM METHYL ALKYL CARBONATE, REACTING CARBONATE WITH TERTIARY ALKANOLAMINE | OSI SPECIALTIES, INC. (US) | 1996-10-08 | — | — | US | claimed |
| US-20260001833-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR REDUCING PRODUCTION OF TRIMETHYLAMINE | CLEVELAND CLINIC FOUND (US) | 2026-01-01 | — | — | US | disclosed |
| WO-2024011238-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR REDUCING PRODUCTION OF TRIMETHYLAMINE | THE CLEVELAND CLINIC FOUNDATION (US) | 2024-01-11 | — | — | WO | disclosed |
| EP-0830336-B1 | PROCESS FOR THE PREPARATION OF TERTIARY AMINOCARBONATES AND AMINOETHERS | CROMPTON CORP (US) | 2003-05-21 | — | — | EP | disclosed |
| EP-0830336-A4 | PROCESS FOR THE PREPARATION OF TERTIARY AMINOCARBONATES AND AMINOETHERS | OSI SPECIALTIES INC (US) | 2000-04-05 | — | — | EP | disclosed |
| EP-0830336-A1 | PROCESS FOR THE PREPARATION OF TERTIARY AMINOCARBONATES AND AMINOETHERS | OSi Specialties, Inc. (US) | 1998-03-25 | — | — | EP | disclosed |
| WO-1996040613-A1 | PROCESS FOR THE PREPARATION OF TERTIARY AMINOCARBONATES AND AMINOETHERS | OSI SPECIALTIES, INC. (US) | 1996-12-19 | — | — | WO | disclosed |
| US-5563288-A | REACTING DIMETHYL CARBONATE WITH ALCOHOL TO FORM METHYL ALKYL CARBONATE, REACTING CARBONATE WITH TERTIARY ALKANOLAMINE | OSI SPECIALTIES, INC. (US) | 1996-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260001833-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR REDUCING PRODUCTION OF TRIMETHYLAMINE | SLC6A6, REN, NHERF1 | CHRM1 202/4885CHRM2 137/4885CHRM4 320/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.