Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 2/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24358311 | 0.88 | FKBP1A (0.42) | FKBP1ANR1H2CYP1A2POLBCYP3A4 | |
| SCHEMBL7728453 | 0.84 | FKBP1A (0.39) | FKBP1ANR1H2CYP1A2POLBCYP3A4 | |
| SCHEMBL9731413 | 0.84 | FKBP1A (0.39) | FKBP1ANR1H2CYP1A2POLBCYP3A4 | |
| SCHEMBL116396 | 0.84 | POLB (0.50) | FKBP1ANR1H2CYP1A2POLBCYP3A4 | |
| SCHEMBL3041685 | 0.84 | POLB (0.50) | FKBP1ANR1H2CYP1A2POLBCYP3A4 | |
| SCHEMBL2202494 | 0.84 | POLB (0.50) | FKBP1ANR1H2CYP1A2POLBCYP3A4 | |
| SCHEMBL16104864 | 0.84 | CYP1A2 (0.40) | FKBP1ANR1H2CYP1A2POLBCYP3A4 | |
| SCHEMBL9636968 | 0.84 | FKBP1A (0.39) | FKBP1ANR1H2CYP1A2POLBCYP3A4 | |
| SCHEMBL9635522 | 0.84 | POLB (0.50) | FKBP1ANR1H2CYP1A2POLBCYP3A4 | |
| SCHEMBL7811172 | 0.84 | CYP1A2 (0.40) | FKBP1ANR1H2CYP1A2POLBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100105685-A1 | S-Nitrosothiol Compounds and Related Derivatives | GALLEON PHARMACEUTICALS, INC. | 2010-04-29 | — | — | US | disclosed |
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105685-A1 | S-Nitrosothiol Compounds and Related Derivatives | NNMT, BHMT2, SQOR | FKBP1A 1689/4885NR1H2 834/4885CYP1A2 338/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.