Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CD81 | P60033 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13409657 | 1.00 | ALDH1A1 (0.34) | ALDH1A1CD81PTGS2ALOX15TSHR | |
| SCHEMBL3928539 | 1.00 | ALDH1A1 (0.34) | ALDH1A1CD81PTGS2ALOX15TSHR | |
| SCHEMBL13409656 | 1.00 | ALDH1A1 (0.34) | ALDH1A1CD81PTGS2ALOX15TSHR | |
| SCHEMBL13409653 | 1.00 | ALDH1A1 (0.34) | ALDH1A1CD81PTGS2ALOX15TSHR | |
| SCHEMBL14364472 | 1.00 | ALDH1A1 (0.34) | ALDH1A1CD81PTGS2ALOX15TSHR | |
| SCHEMBL2211209 | 0.74 | CD81 (0.45) | ALDH1A1CD81ALOX15KMT2A | |
| SCHEMBL14364476 | 0.73 | CNR2 (0.34) | ALDH1A1ALOX15CNR2KMT2A | |
| SCHEMBL1786420 | 0.73 | CNR2 (0.34) | ALDH1A1ALOX15CNR2KMT2A | |
| SCHEMBL1786418 | 0.73 | CNR2 (0.34) | ALDH1A1ALOX15CNR2KMT2A | |
| SCHEMBL13949343 | 0.73 | CNR2 (0.34) | ALDH1A1ALOX15CNR2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240108040-A1 | HIGH INTENSITY SWEETENERS | FIRMENICH INCORPORATED (US) | 2024-04-04 | — | — | US | disclosed |
| US-11758933-B2 | High intensity sweeteners | FIRMENICH INCORPORATED (US) | 2023-09-19 | — | — | US | disclosed |
| EP-3368542-B1 | HIGH INTENSITY SWEETENERS | FIRMENICH INCORPORATED (US) | 2022-06-22 | — | — | EP | disclosed |
| US-11357246-B2 | High intensity sweeteners | FIRMENICH INCORPORATED (US) | 2022-06-14 | — | — | US | disclosed |
| US-20210227863-A1 | HIGH INTENSITY SWEETENERS | SENOMYX, INC. | 2021-07-29 | — | — | US | disclosed |
| EP-3356356-B1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | FIRMENICH INCORPORATED (US) | 2021-05-26 | — | — | EP | disclosed |
| US-10392371-B2 | Compounds useful as modulators of TRPM8 | SENOMYX, INC. (US) | 2019-08-27 | — | — | US | disclosed |
| US-20190177308-A9 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | SENOMYX, INC. | 2019-06-13 | — | — | US | disclosed |
| US-20180273517-A1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | SENOMYX INC (US) | 2018-09-27 | — | — | US | disclosed |
| EP-3368542-A2 | HIGH INTENSITY SWEETENERS | Senomyx, Inc. (US) | 2018-09-05 | — | — | EP | disclosed |
| US-7704941-B2 | Citral derivatives | FLEXITRAL, INC. (US) | 2010-04-27 | — | — | US | disclosed |
| US-7704941-B2 | Citral derivatives | FLEXITRAL, INC. (US) | 2010-04-27 | — | — | US | disclosed |
| US-20080015136-A1 | CITRAL DERIVATIVES | FLEXITRAL, INC. (US) | 2008-01-17 | — | — | US | disclosed |
| US-20080015136-A1 | CITRAL DERIVATIVES | FLEXITRAL, INC. (US) | 2008-01-17 | — | — | US | disclosed |
| US-7309795-B2 | Citral derivatives | FLEXITRAL, INC. | 2007-12-18 | — | — | US | disclosed |
| US-7309795-B2 | Citral derivatives | FLEXITRAL, INC. | 2007-12-18 | — | — | US | disclosed |
| US-20070276152-A1 | Aromachemicals | FLEXITRAL, INC. (US) | 2007-11-29 | — | — | US | disclosed |
| US-20070276152-A1 | Aromachemicals | FLEXITRAL, INC. (US) | 2007-11-29 | — | — | US | disclosed |
| US-20070264340-A1 | Aromachemicals | FLEXITRAL, INC. (US) | 2007-11-15 | — | — | US | disclosed |
| WO-2007120513-A1 | AROMACHEMICALS COMPRISING A NITRILE GROUP | FLEXITRAL, INC. (US) | 2007-10-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240108040-A1 | HIGH INTENSITY SWEETENERS | TAS2R40, TAS2R60, TAS1R1 | ALDH1A1 978/4885CD81 3786/4885PTGS2 2509/4885 |
| US-10392371-B2 | Compounds useful as modulators of TRPM8 | TRPM8, TRPM4, TRPM6 | ALDH1A1 3726/4885CD81 4466/4885PTGS2 1615/4885 |
| US-11357246-B2 | High intensity sweeteners | TAS2R40, TAS2R60, TAS1R1 | ALDH1A1 978/4885CD81 3786/4885PTGS2 2509/4885 |
| US-20070276152-A1 | Aromachemicals | TAS2R1, OR10J3, TAS2R4 | ALDH1A1 189/4885CD81 2907/4885PTGS2 1845/4885 |
| US-20190177308-A9 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | TRPM8, TRPM6, TRPM4 | ALDH1A1 3880/4885CD81 4505/4885PTGS2 1259/4885 |
| US-20180273517-A1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | TRPM8, TRPM6, TRPM4 | ALDH1A1 3880/4885CD81 4505/4885PTGS2 1259/4885 |
| US-20210227863-A1 | HIGH INTENSITY SWEETENERS | TAS2R40, TAS2R60, TAS1R1 | ALDH1A1 978/4885CD81 3786/4885PTGS2 2509/4885 |
| US-11758933-B2 | High intensity sweeteners | TAS2R40, TAS2R60, TAS1R1 | ALDH1A1 978/4885CD81 3786/4885PTGS2 2509/4885 |
| US-20080015136-A1 | CITRAL DERIVATIVES | TAS2R5, TAS2R7, TAS2R8 | ALDH1A1 234/4885CD81 1386/4885PTGS2 1343/4885 |
| US-20070264340-A1 | Aromachemicals | OR10J3, CBR3, OR51E2 | ALDH1A1 173/4885CD81 1155/4885PTGS2 2360/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.