Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 12/20 | 0.53 |
| ▸ | MAPT | P10636 | 11/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 7/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.50 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3069940 | 0.90 | L3MBTL1 (0.65) | L3MBTL1MAPTRAB9AATMHPGD | |
| SCHEMBL3032513 | 0.89 | MAPT (0.54) | L3MBTL1MAPTRAB9AATMHPGD | |
| SCHEMBL3373256 | 0.86 | L3MBTL1 (0.67) | L3MBTL1MAPTRAB9AHPGDNPC1 | |
| SCHEMBL13068898 | 0.86 | ACHE (0.61) | L3MBTL1MAPTRAB9AHPGDNPC1 | |
| SCHEMBL13433961 | 0.85 | L3MBTL1 (0.50) | L3MBTL1MAPTRAB9AATMHPGD | |
| SCHEMBL11963234 | 0.84 | ACHE (0.63) | L3MBTL1MAPTRAB9AHPGDNPC1 | |
| SCHEMBL10196613 | 0.84 | L3MBTL1 (0.67) | L3MBTL1MAPTRAB9AHPGDNPC1 | |
| SCHEMBL16502112 | 0.84 | MAPT (0.61) | L3MBTL1MAPTRAB9AATMHPGD | |
| SCHEMBL3034982 | 0.83 | L3MBTL1 (0.56) | L3MBTL1MAPTRAB9AATMHPGD | |
| SCHEMBL12781859 | 0.83 | L3MBTL1 (0.61) | L3MBTL1MAPTRAB9AHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100056497-A1 | AMIDE DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO., LTD (JP) | 2010-03-04 | — | — | US | disclosed |
| US-20100056497-A1 | AMIDE DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO., LTD (JP) | 2010-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056497-A1 | AMIDE DERIVATIVE | REN, AGTR1, AGTR2 | L3MBTL1 3531/4885MAPT 3478/4885RAB9A 258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.