Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | CFTR | P13569 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.52 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.52 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.52 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.50 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.50 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30118927 | 1.00 | KMT2A (0.61) | KMT2ASLC6A3SLC6A4MAPK1ALDH1A1 | |
| SCHEMBL29644805 | 1.00 | KMT2A (0.61) | KMT2ASLC6A3SLC6A4MAPK1ALDH1A1 | |
| SCHEMBL15830641 | 0.86 | KMT2A (0.53) | KMT2AMAPK1ALDH1A1CFTRKDM4E | |
| SCHEMBL27655231 | 0.86 | KMT2A (0.48) | KMT2ASLC6A3SLC6A4MAPK1ALDH1A1 | |
| SCHEMBL13733857 | 0.85 | SLC6A3 (0.59) | KMT2ASLC6A3SLC6A4ALDH1A1CFTR | |
| SCHEMBL28699640 | 0.85 | CFTR (0.54) | KMT2ASLC6A3SLC6A4MAPK1ALDH1A1 | |
| SCHEMBL28674023 | 0.85 | KMT2A (0.52) | KMT2ASLC6A3SLC6A4MAPK1ALDH1A1 | |
| SCHEMBL3515844 | 0.84 | NR4A2 (0.57) | KMT2AMAPK1ALDH1A1CFTRNR4A2 | |
| SCHEMBL27598660 | 0.83 | SLC6A3 (0.66) | KMT2ASLC6A3SLC6A4ALDH1A1CFTR | |
| SCHEMBL3517715 | 0.83 | RAB9A (0.59) | KMT2AMAPK1ALDH1A1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114835704-B | Sulfonylbenzamide derivatives as BCL-2 inhibitors | 苏州亚盛药业有限公司 | 2023-10-27 | — | — | CN | disclosed |
| US-20100056516-A1 | 1-HYDROXY NAPHTHYRIDINE COMPOUNDS AS ANTI-HIV AGENTS | MERCK SHARP & DOHME CORP. | 2010-03-04 | — | — | US | disclosed |
| CN-101553224-A | Novel imidazothiazoles and imidazoxazoles | ABBOTT LAB (US) | 2009-10-07 | — | — | CN | disclosed |
| CN-1505603-A | Substituted benzoic ac id derivatives exhibiting nf-kappab inhibiting activity | ��һ��������ҩ��ʽ���� | 2004-06-16 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056516-A1 | 1-HYDROXY NAPHTHYRIDINE COMPOUNDS AS ANTI-HIV AGENTS | RNASEH1, RNASE1, RNASEL | KMT2A 2764/4885SLC6A3 3876/4885SLC6A4 3493/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.