Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 8/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.46 |
| ▸ | ELANE | P08246 | 2/20 | 0.45 |
| ▸ | CPT2 | P23786 | 1/20 | 0.38 |
| ▸ | CPT1A | P50416 | 1/20 | 0.38 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3477976 | 0.86 | FAAH (0.54) | FAAHHDAC6PIK3CACYP11B1CYP11B2 | |
| SCHEMBL3477848 | 0.83 | FAAH (0.58) | FAAHHDAC6PIK3CAELANE | |
| SCHEMBL13436723 | 0.81 | FAAH (0.58) | FAAHHDAC6PIK3CAELANE | |
| SCHEMBL3477494 | 0.78 | FAAH (0.60) | FAAHHDAC6PIK3CAELANE | |
| SCHEMBL3475662 | 0.77 | FAAH (0.61) | FAAHHDAC6PIK3CAELANE | |
| SCHEMBL3477397 | 0.77 | FAAH (0.58) | FAAHHDAC6PIK3CAELANE | |
| SCHEMBL3477307 | 0.77 | FAAH (0.66) | FAAHHDAC6PIK3CAELANE | |
| SCHEMBL3475819 | 0.76 | FAAH (0.65) | FAAHHDAC6PIK3CAELANE | |
| SCHEMBL3477409 | 0.76 | FAAH (0.71) | FAAHHDAC6PIK3CAELANE | |
| SCHEMBL13436640 | 0.75 | FAAH (0.61) | FAAHHDAC6PIK3CAELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010039186-A2 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2010-04-08 | — | — | WO | disclosed |