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Sugi Predict / Compounds / SCHEMBL13436723

SCHEMBL13436723

SCHEMBL13436723

CCN1Cc2cc(-c3ccc4oc(NC5CCCCC5)nc4c3)ccc2NC1=O

nearest known ligand 0.58

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ FAAH O00519 8/20 0.58
▸ PIK3CA P42336 2/20 0.46
▸ HDAC6 Q9UBN7 2/20 0.46
▸ BRD4 O60885 1/20 0.42
▸ CREBBP Q92793 1/20 0.42
▸ ELANE P08246 2/20 0.41
▸ SSTR1 P30872 2/20 0.35
▸ SSTR5 P35346 2/20 0.35
▸ HRH1 P35367 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3477848 0.88 FAAH (0.58) FAAHPIK3CAHDAC6BRD4CREBBP
SCHEMBL13436727 0.81 FAAH (0.54) FAAHPIK3CAHDAC6ELANE
SCHEMBL3477976 0.81 FAAH (0.54) FAAHPIK3CAHDAC6ELANE
SCHEMBL3477494 0.74 FAAH (0.60) FAAHPIK3CAHDAC6ELANE
SCHEMBL3478430 0.74 FAAH (0.67) FAAHPIK3CAHDAC6ELANE
SCHEMBL3477409 0.73 FAAH (0.71) FAAHPIK3CAHDAC6ELANE
SCHEMBL3477383 0.73 FAAH (1.00) FAAHPIK3CAHDAC6
SCHEMBL3477307 0.72 FAAH (0.66) FAAHPIK3CAHDAC6ELANE
SCHEMBL3476641 0.72 HDAC6 (0.48) FAAHPIK3CAHDAC6ELANE
SCHEMBL3474444 0.72 FAAH (0.69) FAAHPIK3CAHDAC6SSTR1SSTR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010039186-A2 COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF RENOVIS, INC. (US) 2010-04-08 — — WO disclosed