Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 8/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | ULK1 | O75385 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13436727 | 0.86 | FAAH (0.54) | FAAHHDAC6PIK3CAELANECYP11B1 | |
| SCHEMBL3477848 | 0.83 | FAAH (0.58) | FAAHHDAC6PIK3CAELANE | |
| SCHEMBL13436723 | 0.81 | FAAH (0.58) | FAAHHDAC6PIK3CAELANE | |
| SCHEMBL3477494 | 0.78 | FAAH (0.60) | FAAHHDAC6PIK3CAELANE | |
| SCHEMBL3476641 | 0.78 | HDAC6 (0.48) | FAAHHDAC6PIK3CAELANE | |
| SCHEMBL3477397 | 0.77 | FAAH (0.58) | FAAHHDAC6PIK3CAELANEMAPT | |
| SCHEMBL3477307 | 0.77 | FAAH (0.66) | FAAHHDAC6PIK3CAELANEMAPT | |
| SCHEMBL3477409 | 0.76 | FAAH (0.71) | FAAHHDAC6PIK3CAELANEMAPT | |
| SCHEMBL3475819 | 0.76 | FAAH (0.65) | FAAHHDAC6PIK3CAELANEALDH1A1 | |
| SCHEMBL3477428 | 0.74 | FAAH (0.64) | FAAHHDAC6PIK3CAELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010039186-A2 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2010-04-08 | — | — | WO | disclosed |
| WO-2010039186-A2 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2010-04-08 | — | — | WO | disclosed |