Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 8/20 | 0.58 |
| ▸ | BRD4 | O60885 | 4/20 | 0.51 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | BRD2 | P25440 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13436723 | 0.88 | FAAH (0.58) | FAAHBRD4CREBBPPIK3CAHDAC6 | |
| SCHEMBL3477976 | 0.83 | FAAH (0.54) | FAAHPIK3CAHDAC6ELANE | |
| SCHEMBL13436727 | 0.83 | FAAH (0.54) | FAAHPIK3CAHDAC6ELANE | |
| SCHEMBL3478430 | 0.78 | FAAH (0.67) | FAAHPIK3CAHDAC6ELANE | |
| SCHEMBL3477494 | 0.76 | FAAH (0.60) | FAAHPIK3CAHDAC6ELANE | |
| SCHEMBL3477409 | 0.76 | FAAH (0.71) | FAAHPIK3CAHDAC6ELANE | |
| SCHEMBL3475379 | 0.74 | FAAH (0.66) | FAAHPIK3CAHDAC6ELANE | |
| SCHEMBL3477307 | 0.74 | FAAH (0.66) | FAAHPIK3CAHDAC6ELANE | |
| SCHEMBL3474873 | 0.74 | FAAH (0.60) | FAAHPIK3CAHDAC6ELANE | |
| SCHEMBL3474869 | 0.74 | FAAH (1.00) | FAAHPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010039186-A2 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2010-04-08 | — | — | WO | disclosed |