Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | GRM5 | P41594 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | DRD1 | P21728 | 2/20 | 0.41 |
| ▸ | DRD5 | P21918 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13437758 | 0.87 | POLB (0.43) | SETD7TSHRDRD2DRD3DRD1 | |
| SCHEMBL13462520 | 0.86 | NPC1 (0.50) | SETD7NPC1ACHEDRD2DRD3 | |
| SCHEMBL13437754 | 0.86 | SETD7 (0.66) | SETD7TSHRNPC1DRD2DRD3 | |
| SCHEMBL13437760 | 0.84 | OPRM1 (0.56) | TSHRNPC1GRM5ALOX15ACHE | |
| SCHEMBL13437756 | 0.83 | SETD7 (0.54) | SETD7DRD2DRD3DRD4DRD1 | |
| SCHEMBL14627509 | 0.82 | SETD7 (0.45) | SETD7DRD2DRD3DRD4DRD1 | |
| SCHEMBL13437764 | 0.81 | SETD7 (0.54) | SETD7TSHRDRD2DRD3DRD4 | |
| SCHEMBL13437767 | 0.77 | ALDH1A1 (0.47) | TSHRGRM5DRD2DRD3DRD4 | |
| SCHEMBL13437766 | 0.76 | CCR1 (0.43) | TSHRNPC1GRM5ALOX15DRD2 | |
| SCHEMBL13437765 | 0.76 | DRD2 (0.42) | TSHRDRD2DRD4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7683077-B2 | Piperidine derivative | AJINOMOTO CO., INC. (JP) | 2010-03-23 | — | — | US | disclosed |
| US-7683077-B2 | Piperidine derivative | AJINOMOTO CO., INC. (JP) | 2010-03-23 | — | — | US | disclosed |
| US-20070021460-A1 | Novel piperidine derivative | AJINOMOTO CO., INC. (JP) | 2007-01-25 | — | — | US | disclosed |
| US-20070021460-A1 | Novel piperidine derivative | AJINOMOTO CO., INC. (JP) | 2007-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021460-A1 | Novel piperidine derivative | HTR7, TPH1, HTR5A | SETD7 142/4885TSHR 3421/4885NPC1 849/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.