SCHEMBL1344883

SCHEMBL1344883

CNCn1ccc(=O)[nH]c1=O

nearest known ligand 0.51

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.51
CRBN Q96SW2 3/20 0.48
ALDH1A1 P00352 1/20 0.47
LMNA P02545 1/20 0.47
DUT P33316 10/20 0.47
L3MBTL1 Q9Y468 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31013125 0.81 CRBN (0.57) PKMCRBNALDH1A1LMNADUT
SCHEMBL4278691 0.81 PKM (0.38) PKMCRBNALDH1A1LMNADUT
SCHEMBL24968966 0.79 DUT (0.59) CRBNALDH1A1LMNADUTL3MBTL1
SCHEMBL1923335 0.78 PKM (0.61) PKMCRBNALDH1A1LMNADUT
SCHEMBL4348697 0.77 L3MBTL1 (0.59) PKMCRBNALDH1A1LMNADUT
SCHEMBL6102943 0.75 CRBN (0.56) PKMCRBNALDH1A1LMNADUT
SCHEMBL5796880 0.75 DUT (0.52) PKMCRBNALDH1A1LMNADUT
SCHEMBL17254147 0.75 ALDH1A1 (0.66) PKMCRBNALDH1A1LMNADUT
SCHEMBL7231374 0.74 PKM (0.53) PKMCRBNALDH1A1LMNADUT
SCHEMBL7588438 0.74 PKM (0.49) PKMCRBNALDH1A1LMNADUT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 194 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12545712-B2 C3d cellular and acellular vaccines for the prevention and treatment of cancer THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2026-02-10 US disclosed
US-20250171764-A1 PURIFICATION OF NUCLEIC ACIDS USING COPPER-TITANIUM OXIDES ABBOTT MOLECULAR INC. 2025-05-29 US disclosed
US-12234448-B2 Purification of nucleic acids using titanium oxides ABBOTT MOLECULAR INC. 2025-02-25 US disclosed
WO-2024220575-A2 REGULATING DISEASE OR DISORDER CHARACTERIZED BY ESOPHAGEAL EPITHELIAL PROLIFERATION THROUGH SECRETED FRIZZLED-RELATED PROTEIN 1 (SFRP1) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2024-10-24 WO disclosed
WO-2024220570-A2 C3D IMMUNOTHERAPIES THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2024-10-24 WO disclosed
WO-2024138008-A1 DNA-BASED VECTOR DATA STRUCTURE WITH PARALLEL OPERATIONS Catalog Technologies, Inc. (US) 2024-06-27 WO disclosed
WO-2024137794-A1 DNA-BASED VECTOR DATA STRUCTURE WITH PARALLEL OPERATIONS Catalog Technologies, Inc. (US) 2024-06-27 WO disclosed
EP-4352216-A1 BASE EDITING OF TRANSTHYRETIN GENE Beam Therapeutics Inc. (US) 2024-04-17 EP disclosed
EP-4326334-A1 GLYCAN MODIFIED NUCLEIC ACIDS, METHODS OF PREPARATION, AND THERAPEUTIC USES GanNA Bio, Inc. (US) 2024-02-28 EP disclosed
WO-2024037578-A1 COMPOSITION OF LIPID NANOPARTICLES Suzhou Abogen Biosciences Co., Ltd. (CN) 2024-02-22 WO disclosed
WO-2002066641-A1 PG-3 AND BIALLELIC MARKERS THEREOF GENSET S.A. (FR) 2002-08-29 WO disclosed
WO-2001032885-A9 HUMAN LIPASE MILLENNIUM PHARM INC (US) 2002-05-16 WO disclosed
EP-1159618-A1 PROTEINS FOR DIAGNOSIS AND TREATMENT OF BREAST CANCER Oxford GlycoSciences (UK) Limited (GB) 2001-12-05 EP disclosed
WO-2001053500-A1 METHODS AND MATERIALS RELATING TO STEM CELL GROWTH FACTOR-LIKE POYPEPTIDES AND POLYNUCLEOTIDES HYSEQ, INC. (US) 2001-07-26 WO disclosed
EP-1116032-A1 GPR10 AS A TARGET FOR IDENTIFYING WEIGHT MODULATING COMPOUNDS Millennium Pharmaceuticals, Inc. (US) 2001-07-18 EP disclosed
WO-2001042474-A2 INTERFERON-LIKE MOLECULES AND USES THEREOF AMGEN, INC. (US) 2001-06-14 WO disclosed
WO-2001032885-A2 HUMAN LIPASE MILLENNIUM PHARMACEUTICALS, INC. (US) 2001-05-10 WO disclosed
WO-2000055628-A1 PROTEINS FOR DIAGNOSIS AND TREATMENT OF BREAST CANCER OXFORD GLYCOSCIENCES (UK) LTD. (GB) 2000-09-21 WO disclosed
WO-2000018800-A9 NOVEL SECRETED IMMUNOMODULATORY PROTEINS AND USES THEREOF MILLENNIUM PHARM INC (US) 2000-09-21 WO disclosed
WO-2000017641-A1 GPR10 AS A TARGET FOR IDENTIFYING WEIGHT MODULATING COMPOUNDS MILLENNIUM PHARMACEUTICALS, INC. (US) 2000-03-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12545712-B2 C3d cellular and acellular vaccines for the prevention and treatment of cancer C5AR2, C3AR1, CFD PKM 2694/4885CRBN 690/4885ALDH1A1 4847/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.