SCHEMBL13453022

SCHEMBL13453022

CC1=C(Cl)C(=O)C(Cl)=C(C)C1=O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.53
BCHE P06276 2/20 0.53
ACHE P22303 2/20 0.53
CES1 P23141 2/20 0.53
HPGD P15428 2/20 0.53
ALOX15 P16050 2/20 0.53
HSD17B10 Q99714 2/20 0.53
KDM4E B2RXH2 1/20 0.53
MEN1 O00255 1/20 0.53
ALDH1A1 P00352 1/20 0.53
TP53 P04637 1/20 0.53
CYP3A4 P08684 1/20 0.53
MAPT P10636 1/20 0.53
TSHR P16473 1/20 0.53
ALOX12 P18054 1/20 0.53
MAPK1 P28482 1/20 0.53
RECQL P46063 1/20 0.53
KMT2A Q03164 1/20 0.53
HIF1A Q16665 1/20 0.53
TDP1 Q9NUW8 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7896994 0.90 CES2 (0.60) CES2BCHEACHECES1HPGD
SCHEMBL12465570 0.90 CES2 (0.41) CES2BCHEACHECES1HPGD
SCHEMBL1392670 0.89 CES1 (0.47) CES2BCHEACHECES1HPGD
SCHEMBL5588953 0.81 KDM4E (0.47) CES2BCHEACHECES1HPGD
SCHEMBL20867386 0.81 CES2 (0.53) CES2BCHEACHECES1HPGD
SCHEMBL13114276 0.80 CES2 (0.40) CES2BCHEACHECES1HPGD
SCHEMBL13928036 0.76 CES2 (0.56) CES2BCHEACHECES1HPGD
SCHEMBL2575338 0.74 CES1 (0.57) CES2BCHEACHECES1HPGD
SCHEMBL20458645 0.74 CES2 (0.47) CES2BCHEACHECES1HPGD
SCHEMBL9654039 0.74 ALDH1A1 (0.33) CES2BCHEACHECES1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021133045-A1 POLYMER ELECTROLYTE MEMBRANE, MANUFACTURING METHOD THEREFOR, AND ELECTROCHEMICAL DEVICE COMPRISING SAME 코오롱인더스트리 주식회사 2021-07-01 WO disclosed
US-20190055193-A1 High-Solubility Thioether Quinones U.S. DEPARTMENT OF ENERGY 2019-02-21 US disclosed
US-7683145-B2 Method for the emulsion polymerization of olefins BASF SE (DE) 2010-03-23 US disclosed
US-20090030093-A1 METHOD FOR EMULSION POLYMERISATION OF OLEFINS BASF AKTIENGESSELLSCHAFT (DE) 2009-01-29 US disclosed
US-7417098-B2 Method for emulsion polymerisation of olefins BASF SE (DE) 2008-08-26 US disclosed
US-20080182915-A1 METHOD FOR EMULSION POLYMERISATION OF OLEFINS BASF AKTIENGESELLSCHAFT (DE) 2008-07-31 US disclosed
US-20070043163-A1 Method for emulsion polymerisation of olefins BASF AKTIENGESELLSCHAFT (DE) 2007-02-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080182915-A1 METHOD FOR EMULSION POLYMERISATION OF OLEFINS SQLE, PHOSPHO1, ALOX15 CES2 1414/4885BCHE 1809/4885ACHE 1354/4885
US-20070043163-A1 Method for emulsion polymerisation of olefins PHOSPHO1, SQLE, ALOX15 CES2 1710/4885BCHE 1571/4885ACHE 1056/4885
US-20190055193-A1 High-Solubility Thioether Quinones SQOR, TST, NDUFS3 CES2 2559/4885BCHE 2298/4885ACHE 3312/4885
US-20090030093-A1 METHOD FOR EMULSION POLYMERISATION OF OLEFINS PHOSPHO1, SQLE, ALOX15 CES2 1710/4885BCHE 1571/4885ACHE 1056/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.