Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.44 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SCN1A | P35498 | 1/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2170893 | 1.00 | HPGD (0.50) | HPGDSLC6A3MT-CO2PTGS1PTGS2 | |
| SCHEMBL262458 | 1.00 | HPGD (0.50) | HPGDSLC6A3MT-CO2PTGS1PTGS2 | |
| Hydrochloric Acid SCHEMBL6792900 | 0.98 | HPGD (0.49) | HPGDSLC6A3MT-CO2PTGS1PTGS2 | |
| SCHEMBL11130803 | 0.88 | HPGD (0.53) | HPGDMT-CO2PTGS1PTGS2CXCR1 | |
| SCHEMBL12896284 | 0.88 | HPGD (0.53) | HPGDMT-CO2PTGS1PTGS2CXCR1 | |
| SCHEMBL1000872 | 0.84 | LMNA (0.40) | HPGDSLC6A3PTGS2CXCR1CXCR2 | |
| SCHEMBL22838087 | 0.82 | KMT2A (0.55) | HPGDSLC6A3KMT2ASCN1ASCN2A | |
| SCHEMBL1747458 | 0.82 | ESR1 (0.56) | HPGDMT-CO2PTGS1PTGS2KMT2A | |
| SCHEMBL3526852 | 0.82 | ALDH1A1 (0.56) | SLC6A3KMT2ASCN1ASCN2ASCN3A | |
| SCHEMBL12424105 | 0.82 | HPGD (0.51) | HPGDMT-CO2PTGS1PTGS2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025067168-A1 | AZA FUSED RING COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 苏州爱科百发生物医药技术有限公司 | 2025-04-03 | — | — | WO | disclosed |
| CN-102159558-B | 2-arylpropionic acids and derivatives thereof and pharmaceutical compositions containing said compounds | DOMPE SPA | 2015-01-07 | — | — | CN | disclosed |
| US-8063242-B2 | for treatment of neutrofil-dependent pathologies such as psoriasis, ulcerative colitis, melanoma, chronic obstructive pulmonary disease (COPD), bollous pemphigo, rheumatoid arthritis, idiopathic fibrosis, glomerulonephritis; prevention and treatment of damages caused by ischemia and reperfusion | DOMPE PHA.R.MA S.P.A. (IT) | 2011-11-22 | — | — | US | disclosed |
| US-20110207785-A1 | 2-Aryl-Propionic Acids and Derivatives and Pharmaceutical Compositions Containing Them | DOMPE S.P.A. (IT) | 2011-08-25 | — | — | US | disclosed |
| CN-102159558-A | 2-arylpropionic acids and derivatives thereof and pharmaceutical compositions containing said compounds | DOMPE SPA | 2011-08-17 | — | — | CN | disclosed |
| EP-2346841-A2 | 2-ARYL-PROPIONIC ACIDS AND DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Dompe S.p.A. (IT) | 2011-07-27 | — | — | EP | disclosed |
| EP-2229942-A1 | 2-Aryl-propionic acids and pharmaceutical compositions containing them | Dompe S.p.A. (IT) | 2010-09-22 | — | — | EP | disclosed |
| EP-1455773-B1 | 2-ARYL-PROPIONIC ACIDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DOMPE PHA R MA SPA RES & MFG (IT) | 2009-11-04 | — | — | EP | disclosed |
| CN-1286835-C | Phenylacetamido-thiazole derivatives, process for their preparation and their use as antitumor agents | PHARMACIA ITALIA SPA (IT) | 2006-11-29 | — | — | CN | disclosed |
| US-20050038119-A1 | 2-Aryl-propionic acids and pharmaceutical compositions containing them | DOMPÉ FARMACEUTICI S.P.A. (IT) | 2005-02-17 | — | — | US | disclosed |
| US-20040235919-A1 | Phenylacetamido-thiazole derivatives, process for the preparation and their use as antitumor agents | PFIZER ITALIA S.R.I. (IT) | 2004-11-25 | — | — | US | disclosed |
| CN-1531535-A | Phenylacetamido-thiazole derivatives, process for their preparation and their use as antitumor agents | — | 2004-09-22 | — | — | CN | disclosed |
| EP-1455773-A1 | 2-ARYL-PROPIONIC ACIDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Dompé S.P.A. (IT) | 2004-09-15 | — | — | EP | disclosed |
| WO-2003043625-A1 | 2-ARYL-PROPIONIC ACIDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DOMPE S.P.A. (IT) | 2003-05-30 | — | — | WO | disclosed |
| US-3973022-A | Quinolineacetic acid compositions | CIBA-GEIGY CORPORATION (US) | 1976-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110207785-A1 | 2-Aryl-Propionic Acids and Derivatives and Pharmaceutical Compositions Containing Them | CXCR3, F2RL1, FPR2 | HPGD 413/4885SLC6A3 2291/4885MT-CO2 1235/4885 |
| US-20040235919-A1 | Phenylacetamido-thiazole derivatives, process for the preparation and their use as antitumor agents | CDK2, CDK1, CDKN1A | HPGD 1364/4885SLC6A3 2679/4885MT-CO2 3257/4885 |
| US-20050038119-A1 | 2-Aryl-propionic acids and pharmaceutical compositions containing them | CXCR2, FPR1, CCR2 | HPGD 330/4885SLC6A3 4294/4885MT-CO2 1702/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.