Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 3/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.34 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12939881 | 0.84 | FTO (0.50) | FTOPDK2MEN1KMT2AMAPT | |
| SCHEMBL12018638 | 0.83 | FTO (0.50) | FTOMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL418120 | 0.76 | MAPT (0.42) | FTOPDK2MEN1KMT2AMAPT | |
| SCHEMBL13069672 | 0.76 | ALDH1A1 (0.46) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL12957840 | 0.72 | PDK2 (0.42) | PDK2MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL31672202 | 0.68 | MAPT (0.52) | FTOPDK2MEN1KMT2AMAPT | |
| SCHEMBL21585350 | 0.68 | MAPT (0.47) | FTOPDK2MEN1KMT2AMAPT | |
| SCHEMBL8984527 | 0.68 | MAPT (0.52) | FTOPDK2MEN1KMT2AMAPT | |
| SCHEMBL12288857 | 0.68 | LMNA (0.38) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL12649210 | 0.68 | FTO (0.37) | FTOMEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010028156-A2 | DUAL MODALITY DETECTION OF APOPTOSIS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2010-03-11 | — | — | WO | disclosed |