Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.56 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.47 |
| ▸ | GABRP | O00591 | 1/20 | 0.47 |
| ▸ | GABRD | O14764 | 1/20 | 0.47 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.47 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.47 |
| ▸ | GABRE | P78334 | 1/20 | 0.47 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.47 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.47 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.47 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 4/20 | 0.43 |
| ▸ | CHUK | O15111 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29581491 | 0.81 | MAPT (0.63) | MAPT | |
| SCHEMBL16645244 | 0.81 | MAPT (0.63) | MAPT | |
| SCHEMBL20128568 | 0.80 | MAPT (0.63) | MAPTKIF11ACHECHUK | |
| Flortaucipir SCHEMBL29548430 | 0.79 | MAPT (0.77) | MAPTKIF11ACHECHUK | |
| Flortaucipir F 18 SCHEMBL29379518 | 0.79 | MAPT (0.77) | MAPTKIF11ACHECHUK | |
| Flortaucipir SCHEMBL29439901 | 0.79 | MAPT (0.77) | MAPTKIF11ACHECHUK | |
| Flortaucipir F 18 SCHEMBL13640613 | 0.79 | MAPT (0.77) | MAPTKIF11ACHECHUK | |
| Flortaucipir SCHEMBL29773835 | 0.79 | MAPT (0.77) | MAPTKIF11ACHECHUK | |
| Flortaucipir F 18 SCHEMBL29707635 | 0.79 | MAPT (0.77) | MAPTKIF11ACHECHUK | |
| Flortaucipir SCHEMBL14053964 | 0.79 | MAPT (0.77) | MAPTKIF11ACHECHUK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2799091-B1 | System, device and method for preparing tracers and transferring materials during radiosynthesis | LILLY CO ELI (US) | 2016-07-13 | — | — | EP | claimed |
| US-20150030540-A1 | Imaging agents for detecting neurological dysfunction | LILLY CO ELI (US) | 2015-01-29 | — | — | US | claimed |
| US-8932557-B2 | Imaging agents for detecting neurological dysfunction | ELI LILLY AND COMPANY (US) | 2015-01-13 | — | — | US | claimed |
| EP-2799091-A2 | System, device and method for preparing tracers and transferring materials during radiosynthesis | Siemens Medical Solutions USA, Inc. (US) | 2014-11-05 | — | — | EP | claimed |
| US-10639608-B2 | System, device and method for preparing tracers and transferring materials during radiosynthesis | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2020-05-05 | — | — | US | disclosed |
| US-9546167-B2 | Radiosynthesis of tau radiopharmaceuticals | THE GENERAL HOSPITAL CORPORATION (US) | 2017-01-17 | — | — | US | disclosed |
| US-20160228586-A1 | Compounds and Their Use for Preparation of Tau Imaging Agents and Tau Imaging Formulations | LILLY CO ELI (US) | 2016-08-11 | — | — | US | disclosed |
| US-20160228586-A1 | Compounds and Their Use for Preparation of Tau Imaging Agents and Tau Imaging Formulations | LILLY CO ELI (US) | 2016-08-11 | — | — | US | disclosed |
| US-20160228586-A1 | Compounds and Their Use for Preparation of Tau Imaging Agents and Tau Imaging Formulations | LILLY CO ELI (US) | 2016-08-11 | — | — | US | disclosed |
| EP-3049414-A1 | COMPOUNDS AND THEIR USE FOR PREPARATION OF TAU IMAGING AGENTS AND TAU IMAGING FORMULATIONS | Eli Lilly and Company (US) | 2016-08-03 | — | — | EP | disclosed |
| US-20160214982-A1 | Radiosynthesis of Tau Radiopharmaceuticals | THE GENERAL HOSPITAL CORPORATION | 2016-07-28 | — | — | US | disclosed |
| EP-2799091-B1 | System, device and method for preparing tracers and transferring materials during radiosynthesis | LILLY CO ELI (US) | 2016-07-13 | — | — | EP | disclosed |
| US-20150030540-A1 | Imaging agents for detecting neurological dysfunction | LILLY CO ELI (US) | 2015-01-29 | — | — | US | disclosed |
| US-20150030540-A1 | Imaging agents for detecting neurological dysfunction | LILLY CO ELI (US) | 2015-01-29 | — | — | US | disclosed |
| US-8932557-B2 | Imaging agents for detecting neurological dysfunction | ELI LILLY AND COMPANY (US) | 2015-01-13 | — | — | US | disclosed |
| US-8932557-B2 | Imaging agents for detecting neurological dysfunction | ELI LILLY AND COMPANY (US) | 2015-01-13 | — | — | US | disclosed |
| EP-2799091-A2 | System, device and method for preparing tracers and transferring materials during radiosynthesis | Siemens Medical Solutions USA, Inc. (US) | 2014-11-05 | — | — | EP | disclosed |
| US-20120302755-A1 | Imaging Agents for Detecting Neurological Dysfunction | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2012-11-29 | — | — | US | disclosed |
| US-20120283490-A1 | System, Device and Method for Preparing Tracers and Transferring Materials During Radiosynthesis | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2012-11-08 | — | — | US | disclosed |
| EP-2511006-A2 | System, device and method for preparing tracers and transferring materials during radiosynthesis | Siemens Medical Solutions USA, Inc. (US) | 2012-10-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160214982-A1 | Radiosynthesis of Tau Radiopharmaceuticals | MAPT, HTR7, TTBK2 | MAPT 1/4885GABRA1 1387/4885GABRG2 2707/4885 |
| US-20120283490-A1 | System, Device and Method for Preparing Tracers and Transferring Materials During Radiosynthesis | TERT, VHL, REV1 | MAPT 3700/4885GABRA1 4207/4885GABRG2 4135/4885 |
| US-20160228586-A1 | Compounds and Their Use for Preparation of Tau Imaging Agents and Tau Imaging Formulations | MAPT, PSEN1, PSEN2 | MAPT 1/4885GABRA1 1759/4885GABRG2 2161/4885 |
| US-10639608-B2 | System, device and method for preparing tracers and transferring materials during radiosynthesis | TERT, VHL, REV1 | MAPT 3700/4885GABRA1 4207/4885GABRG2 4135/4885 |
| US-20150030540-A1 | Imaging agents for detecting neurological dysfunction | SLC18A3, TSPO, CHAT | MAPT 36/4885GABRA1 180/4885GABRG2 990/4885 |
| US-20120302755-A1 | Imaging Agents for Detecting Neurological Dysfunction | SLC18A3, TSPO, CHAT | MAPT 36/4885GABRA1 180/4885GABRG2 990/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.