Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 1.00 |
| ▸ | MAPT | P10636 | 5/20 | 1.00 |
| ▸ | NPC1 | O15118 | 4/20 | 1.00 |
| ▸ | GLA | P06280 | 3/20 | 1.00 |
| ▸ | GAA | P10253 | 3/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 1.00 |
| ▸ | APP | P05067 | 5/20 | 0.69 |
| ▸ | MMP9 | P14780 | 2/20 | 0.69 |
| ▸ | MMP8 | P22894 | 2/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.68 |
| ▸ | TP53 | P04637 | 2/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.68 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.68 |
| ▸ | RELA | Q04206 | 1/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | PKM | P14618 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29658189 | 1.00 | RAB9A (1.00) | RAB9AKDM4EMAPTNPC1GLA | |
| SCHEMBL27494065 | 0.98 | RAB9A (0.96) | RAB9AKDM4EMAPTNPC1GLA | |
| SCHEMBL1518992 | 0.98 | RAB9A (0.96) | RAB9AKDM4EMAPTNPC1GLA | |
| SCHEMBL8994279 | 0.92 | RAB9A (0.84) | RAB9AKDM4EMAPTNPC1GLA | |
| SCHEMBL29474819 | 0.90 | RAB9A (0.81) | RAB9AKDM4EMAPTNPC1GLA | |
| SCHEMBL366824 | 0.90 | RAB9A (0.81) | RAB9AKDM4EMAPTNPC1GLA | |
| SCHEMBL24295138 | 0.88 | RAB9A (0.79) | RAB9AKDM4EMAPTNPC1GLA | |
| SCHEMBL31686431 | 0.85 | KDM4E (0.73) | RAB9AKDM4EMAPTNPC1GLA | |
| SCHEMBL25239036 | 0.85 | KDM4E (0.73) | RAB9AKDM4EMAPTNPC1GLA | |
| SCHEMBL754574 | 0.85 | RAB9A (0.73) | RAB9AKDM4EMAPTNPC1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 194 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114478514-B | Fluorescent molecular probe with aggregation-induced emission characteristic and preparation method and application thereof | 湖南省肿瘤医院 | 2023-04-18 | — | — | CN | claimed |
| CN-110172337-B | Benzothiazole derivative fluorescent probe and preparation method and application thereof | 南京师范大学 | 2022-09-13 | — | — | CN | claimed |
| CN-114634507-B | Fluorescent probe for detecting zinc ions and preparation method thereof | 烟台大学 | 2022-08-23 | — | — | CN | claimed |
| CN-113004266-B | Fluorescent probe based on benzothiazolyl phenol-hemicyanine system and preparation method and application thereof | 陕西中医药大学 | 2022-07-12 | — | — | CN | claimed |
| CN-114634507-A | Fluorescent probe for detecting zinc ions and preparation method thereof | 烟台大学 | 2022-06-17 | — | — | CN | claimed |
| CN-114478514-A | Fluorescent molecular probe with aggregation-induced emission characteristic and preparation method and application thereof | 湖南省肿瘤医院 | 2022-05-13 | — | — | CN | claimed |
| CN-113004266-A | Fluorescent probe based on benzothiazolyl phenol-hemicyanine system and preparation method and application thereof | 陕西中医药大学 | 2021-06-22 | — | — | CN | claimed |
| CN-110172337-A | A kind of benzothiazole derivant fluorescence probe and its preparation method and application | 南京师范大学 | 2019-08-27 | — | — | CN | claimed |
| CN-104761536-B | Method of synthesizing 2-substituted benzothiazole-type derivative | 内蒙古工业大学 | 2017-05-10 | — | — | CN | claimed |
| CN-104761536-A | Method of synthesizing 2-substituted benzothiazole-type derivative | UNIV INNER MONGOLIA TECHNOLOGY | 2015-07-08 | — | — | CN | claimed |
| US-20140378515-A1 | IMMUNOSUPPRESSIVE COMPOUNDS | MESAIK MUHAMMAD A (PK) | 2014-12-25 | — | — | US | claimed |
| CN-103937487-A | Phosphorescent fluorinion probe, preparation and applications thereof | UNIV NANJING POSTS & TELECOMM | 2014-07-23 | — | — | CN | claimed |
| WO-2012108689-A2 | NOVEL COMPOUND HAVING SKIN-WHITENING, ANTI-OXIDIZING AND PPAR ACTIVITIES AND MEDICAL USE THEREFOR | 부산대학교 산학협력단 (KR) | 2012-08-16 | — | — | WO | claimed |
| US-8063204-B2 | Benzothiazole and benzoxazole linked pyrrolo[2,1-c] [1, 4] benzodiazepine hybrids as novel antitumour agents and process for the preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2011-11-22 | — | — | US | claimed |
| US-20100113771-A1 | NOVEL BENZOTHIAZOLE AND BENZOXAZOLE LINKED PYRROLO[2,1-C] [1, 4] BENZODIAZEPINE HYBRIDS AS NOVEL ANTITUMOUR AGENTS AND PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2010-05-06 | — | — | US | claimed |
| WO-2008099416-A2 | NOVEL BENZOTHIAZOLE AND BENZOXAZOLE LINKED PYRROLO[2,1-C] [1, 4] BENZODIAZEPINE HYBRIDS AS NOVEL ANTITUMOUR AGENTS AND PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2008-08-21 | — | — | WO | claimed |
| EP-0652273-B1 | Organic material for electroluminescent device and electroluminescent device | SHINKO ELECTRIC IND CO (JP) | 1998-02-11 | — | — | EP | claimed |
| EP-0721336-A1 | BENZAZOLE COMPOUNDS FOR USE IN THERAPY | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1996-07-17 | — | — | EP | claimed |
| WO-1995006469-A1 | BENZAZOLE COMPOUNDS FOR USE IN THERAPY | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1995-03-09 | — | — | WO | claimed |
| EP-0455471-A2 | Improved chemiluminescent reagents and methods | Hitachi Chemical Co., Ltd. (JP) | 1991-11-06 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140378515-A1 | IMMUNOSUPPRESSIVE COMPOUNDS | IL4, TLR4, NOX4 | RAB9A 2337/4885KDM4E 69/4885MAPT 1490/4885 |
| US-20100113771-A1 | NOVEL BENZOTHIAZOLE AND BENZOXAZOLE LINKED PYRROLO[2,1-C] [1, 4] BENZODIAZEPINE HYBRIDS AS NOVEL ANTITUMOUR AGENTS AND PROCESS FOR THE PREPARATION THEREOF | GABRA1, GABRA4, GABRA5 | RAB9A 1405/4885KDM4E 1064/4885MAPT 2534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.