Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9216581 | 0.85 | KDM4E (0.64) | TDP1KDM4EGAALMNAALDH1A1 | |
| SCHEMBL13469365 | 0.85 | L3MBTL1 (0.46) | TDP1KDM4EGAALMNAALDH1A1 | |
| SCHEMBL23411350 | 0.83 | KDM4E (0.64) | KDM4EGAALMNAALDH1A1HPGD | |
| SCHEMBL29891520 | 0.83 | KDM4E (0.64) | KDM4EGAALMNAALDH1A1HPGD | |
| SCHEMBL6232527 | 0.80 | ALDH1A1 (0.52) | KDM4EGAALMNAALDH1A1HPGD | |
| SCHEMBL7162258 | 0.79 | KDM4E (0.47) | TDP1KDM4EGAALMNAALDH1A1 | |
| SCHEMBL16534208 | 0.77 | TDP1 (0.41) | TDP1LMNAALDH1A1HTTMAPK1 | |
| SCHEMBL568368 | 0.77 | ALDH1A1 (0.56) | KDM4EGAALMNAALDH1A1HPGD | |
| SCHEMBL30099730 | 0.77 | ALDH1A1 (0.56) | KDM4EGAALMNAALDH1A1HPGD | |
| SCHEMBL13469509 | 0.76 | TDP1 (0.38) | TDP1GAALMNAHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3354640-A2 | MIF INHIBITORS AND THEIR USES | Innovimmune Biotherapeutics, Inc. (US) | 2018-08-01 | — | — | EP | disclosed |
| EP-3354640-A2 | MIF INHIBITORS AND THEIR USES | Innovimmune Biotherapeutics, Inc. (US) | 2018-08-01 | — | — | EP | disclosed |
| EP-2696682-B1 | MIF INHIBITORS AND THEIR USES | INNOVIMMUNE BIOTHERAPEUTICS INC (US) | 2018-03-21 | — | — | EP | disclosed |
| EP-2696682-B1 | MIF INHIBITORS AND THEIR USES | INNOVIMMUNE BIOTHERAPEUTICS INC (US) | 2018-03-21 | — | — | EP | disclosed |
| US-9133164-B2 | MIF inhibitors and their uses | INNOV88 LLC (US) | 2015-09-15 | — | — | US | disclosed |
| US-20150065480-A1 | MIF INHIBITORS AND THEIR USES | INNOVIMMUNE BIOTHERAPEUTICS, INC. (US) | 2015-03-05 | — | — | US | disclosed |
| WO-2012142498-A2 | MIF INHIBITORS AND THEIR USES | INNOVIMMUNE BIOTHERAPEUTICS, INC. (US) | 2012-10-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150065480-A1 | MIF INHIBITORS AND THEIR USES | MIF, SERPINB1, HMGB2 | TDP1 3472/4885KDM4E 4189/4885GAA 1974/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.