Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 8/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.42 |
| ▸ | USP2 | O75604 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 5/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.40 |
| ▸ | ATM | Q13315 | 7/20 | 0.39 |
| ▸ | GLA | P06280 | 6/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12836995 | 0.78 | ALDH1A1 (0.45) | ALDH1A1KDM4EMAPTL3MBTL1HPGD | |
| SCHEMBL13179036 | 0.74 | ABCB1 (0.56) | ALDH1A1KDM4EMAPTL3MBTL1HPGD | |
| SCHEMBL13015811 | 0.73 | MEN1 (0.61) | ALDH1A1KDM4EMAPTL3MBTL1HPGD | |
| SCHEMBL13820288 | 0.73 | ABCB1 (0.59) | ALDH1A1KDM4EMAPTL3MBTL1HPGD | |
| SCHEMBL14338738 | 0.72 | MEN1 (0.57) | ALDH1A1KDM4EMAPTL3MBTL1HPGD | |
| SCHEMBL10040697 | 0.72 | ABCB1 (0.71) | ALDH1A1KDM4EMAPTL3MBTL1HPGD | |
| SCHEMBL13015810 | 0.71 | MEN1 (0.60) | ALDH1A1KDM4EMAPTL3MBTL1HPGD | |
| SCHEMBL13015812 | 0.70 | MEN1 (0.57) | ALDH1A1KDM4EMAPTL3MBTL1HPGD | |
| SCHEMBL14534275 | 0.70 | ABCB1 (0.54) | ALDH1A1MAPTHPGDSMN1; SMN2MEN1 | |
| SCHEMBL14263967 | 0.70 | ABCB1 (0.51) | ALDH1A1KDM4EMAPTL3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100029010-A1 | Diaminorhodamine Derivative | Nagano, Tetsuo (JP) | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029010-A1 | Diaminorhodamine Derivative | NOS2, NOS1, NOS3 | ALDH1A1 1638/4885KDM4E 1388/4885MAPT 4542/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.