Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15746390 | 0.82 | MEN1 (0.34) | MGAMGAASIMGAM2 | |
| SCHEMBL805100 | 0.82 | — | — | |
| SCHEMBL804999 | 0.82 | — | — | |
| SCHEMBL864303 | 0.82 | — | — | |
| SCHEMBL15745788 | 0.81 | MEN1 (0.33) | GAA | |
| SCHEMBL18726371 | 0.80 | TSHR (0.45) | CA14SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4589404 | 0.80 | MGAM (0.44) | MGAMGAASIMGAM2 | |
| SCHEMBL807266 | 0.80 | TSHR (0.45) | CA14SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL15156949 | 0.80 | MGAM (0.44) | MGAMGAASIMGAM2 | |
| SCHEMBL19190109 | 0.78 | HCAR2 (0.38) | CHRNB2CHRNA4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8765162-B2 | Poly(amide) and poly(ester-amide) polymers and drug delivery particles and coatings containing same | ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) | 2014-07-01 | — | — | US | disclosed |
| US-8323676-B2 | Poly(ester-amide) and poly(amide) coatings for implantable medical devices for controlled release of a protein or peptide and a hydrophobic drug | ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) | 2012-12-04 | — | — | US | disclosed |
| US-20100047319-A1 | Biodegradable Poly(Ester-Amide) And Poly(Amide) Coatings For Implantable Medical Devices With Enhanced Bioabsorption Times | ABBOTT CARDIOVASCULAR SYSTEMS INC. | 2010-02-25 | — | — | US | disclosed |
| US-20090324671-A1 | Poly(Amide) And Poly(Ester-Amide) Polymers And Drug Delivery Particles And Coatings Containing Same | ABBOTT CARDIOVASCULAR SYSTEMS INC. | 2009-12-31 | — | — | US | disclosed |
| US-20090324672-A1 | Poly(Ester-Amide) And Poly(Amide) Coatings For Implantable Medical Devices For Controlled Release Of A Protein Or Peptide And A Hydrophobic Drug | ABBOTT CARDIOVASCULAR SYSTEMS INC. | 2009-12-31 | — | — | US | disclosed |
| US-20090258028-A1 | Methods Of Forming Coatings For Implantable Medical Devices For Controlled Release Of A Peptide And A Hydrophobic Drug | ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) | 2009-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100047319-A1 | Biodegradable Poly(Ester-Amide) And Poly(Amide) Coatings For Implantable Medical Devices With Enhanced Bioabsorption Times | SLC10A2, SI, PAM | CA14 201/4885CHRNB2 4221/4885CHRNA4 3970/4885 |
| US-20090324672-A1 | Poly(Ester-Amide) And Poly(Amide) Coatings For Implantable Medical Devices For Controlled Release Of A Protein Or Peptide And A Hydrophobic Drug | CUTA, NAPA, GHITM | CA14 2287/4885CHRNB2 4380/4885CHRNA4 4148/4885 |
| US-20090258028-A1 | Methods Of Forming Coatings For Implantable Medical Devices For Controlled Release Of A Peptide And A Hydrophobic Drug | HDGF, ADM2, HGF | CA14 1095/4885CHRNB2 2904/4885CHRNA4 3836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.