SCHEMBL13490488

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13490646	0.83	LMNA (0.41)	LMNAPOLBSIGMAR1KMT2AMEN1
	SCHEMBL13490484	0.81	KMT2A (0.39)	LMNAPOLBSIGMAR1KMT2AMEN1
	SCHEMBL13490470	0.79	DRD2 (0.42)	LMNAPOLBSIGMAR1KDM4EALDH1A1
	SCHEMBL13490577	0.77	LMNA (0.47)	LMNAPOLBSIGMAR1TSHRMAPK1
	SCHEMBL13592727	0.75	SIGMAR1 (0.40)	LMNASIGMAR1KMT2AMEN1MAPK1
	SCHEMBL171533	0.74	DRD2 (0.37)	SIGMAR1KMT2AMEN1KDM4EALDH1A1
	SCHEMBL169524	0.72	ALDH1A1 (0.39)	LMNASIGMAR1MAPK1ALDH1A1MAPT
	SCHEMBL10640414	0.72	SIGMAR1 (0.52)	LMNAPOLBSIGMAR1MC4RDRD4
	SCHEMBL171149	0.71	SIGMAR1 (0.50)	LMNASIGMAR1KMT2AMEN1MAPK1
	SCHEMBL169427	0.71	TRPV6 (0.37)	SIGMAR1KMT2AMEN1KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.