Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 13/20 | 0.51 |
| ▸ | CNR2 | P34972 | 11/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.45 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13490773 | 0.84 | KMT2A (0.45) | HSD17B1HSD17B2LMNAHPGDALDH1A1 | |
| SCHEMBL13490816 | 0.84 | FFAR1 (0.54) | CNR1CNR2FFAR1PPARGPPARD | |
| SCHEMBL13490815 | 0.80 | BRD4 (0.47) | CNR1CNR2ALDH1A1SMN1; SMN2FFAR1 | |
| SCHEMBL13008060 | 0.77 | MAPT (0.47) | LMNAALDH1A1MAPTPPARGPPARA | |
| SCHEMBL13490806 | 0.77 | MTNR1B (0.59) | CNR1CNR2ALDH1A1SMN1; SMN2 | |
| SCHEMBL13490811 | 0.75 | MTNR1B (0.65) | CNR1CNR2ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8325496 | 0.75 | CNR1 (0.52) | CNR1CNR2LMNAHPGDALDH1A1 | |
| SCHEMBL13490807 | 0.75 | CNR1 (0.44) | CNR1CNR2ALDH1A1 | |
| SCHEMBL88961 | 0.75 | ALDH1A1 (0.48) | CNR1CNR2ALDH1A1 | |
| SCHEMBL88959 | 0.75 | ALDH1A1 (0.44) | CNR1CNR2LMNAHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100029647-A1 | 3,4,(5)-SUBSTITUTED TETRAHYDROPHYRIDINES | NOVARTIS AG (CH) | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029647-A1 | 3,4,(5)-SUBSTITUTED TETRAHYDROPHYRIDINES | REN, PAH, ACE | CNR1 2437/4885CNR2 2478/4885HDAC3 1775/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.